What does netrin mean?
Definitions for netrin
netrin
This dictionary definitions page includes all the possible meanings, example usage and translations of the word netrin.
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Wiktionary
netrinnoun
Any of a class of proteins involved in axon guidance
Wikidata
Netrin
Netrins are a class of proteins involved in axon guidance. They are named after the Sanskrit word "netr", which means "one who guides." Netrins are genetically conserved across nematode worms, fruitflies, frogs, and mice. Structurally, netrin resembles the extracellular matrix protein laminin. Netrins are chemotropic; a growing axon will either move towards or away from a higher concentration of netrin. Though the detailed mechanism of axon guidance is not fully understood, it is known that netrin attraction is mediated through UNC-40/DCC cell surface receptors and repulsion is mediated through UNC-5 receptors. Netrins also act as growth factors, encouraging cell growth activities in target cells. Mice deficient in netrin fail to form the hippocampal comissure or the corpus callosum. A proposed model for netrin activity in the spinal column of developing human embryos is that netrins are released by the floor plate and then are picked up by receptor proteins embedded in the growth cones of axons belonging to neurons in the developing spinal column. The bodies of these neurons remain stationary while the axons follow a path defined by netrins, eventually connecting to neurons inside the embryonic brain by developing synapses. Research supports that new axons tend to follow previously traced pathways, rather than being guided by netrins or related chemotropic factors.
Anagrams for netrin »
intern
tinner
Numerology
Chaldean Numerology
The numerical value of netrin in Chaldean Numerology is: 4
Pythagorean Numerology
The numerical value of netrin in Pythagorean Numerology is: 8
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"netrin." Definitions.net. STANDS4 LLC, 2024. Web. 26 Apr. 2024. <https://www.definitions.net/definition/netrin>.
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