Definitions for methylation
methy·la·tion

WiktionaryRate this definition:0.0 / 0 votes

1. methylationnoun

   the addition of a methyl group to a molecule

2. methylationnoun

   the addition of a methyl group to cytosine and adenine residues in DNA that leads to the epigenetic modification of DNA and the reduction of gene expression and protein production

3. Etymology: methyl + -ation

WikipediaRate this definition:0.0 / 0 votes

1. Methylation

   In the chemical sciences, methylation denotes the addition of a methyl group on a substrate, or the substitution of an atom (or group) by a methyl group. Methylation is a form of alkylation, with a methyl group replacing a hydrogen atom. These terms are commonly used in chemistry, biochemistry, soil science, and the biological sciences. In biological systems, methylation is catalyzed by enzymes; such methylation can be involved in modification of heavy metals, regulation of gene expression, regulation of protein function, and RNA processing. In vitro methylation of tissue samples is also one method for reducing certain histological staining artifacts. The reverse of methylation is demethylation.

WikidataRate this definition:2.0 / 2 votes

1. Methylation

   In the chemical sciences, methylation denotes the addition of a methyl group to a substrate or the substitution of an atom or group by a methyl group. Methylation is a form of alkylation with a methyl group, rather than a larger carbon chain, replacing a hydrogen atom. These terms are commonly used in chemistry, biochemistry, soil science, and the biological sciences. In biological systems, methylation is catalyzed by enzymes; such methylation can be involved in modification of heavy metals, regulation of gene expression, regulation of protein function, and RNA metabolism. Methylation of heavy metals can also occur outside of biological systems. Chemical methylation of tissue samples is also one method for reducing certain histological staining artifacts.

U.S. National Library of MedicineRate this definition:5.0 / 1 vote

1. Methylation

   Addition of methyl groups. In histo-chemistry methylation is used to esterify carboxyl groups and remove sulfate groups by treating tissue sections with hot methanol in the presence of hydrochloric acid. (From Stedman, 25th ed)

How to pronounce methylation?

1. Alex

   US English

   David

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   Mark

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   Daniel

   British

   Libby

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   Mia

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   Karen

   Australian

   Hayley

   Australian

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   Neerja

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   Oliver

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How to say methylation in sign language?

Numerology

1. Chaldean Numerology

   The numerical value of methylation in Chaldean Numerology is: 4

2. Pythagorean Numerology

   The numerical value of methylation in Pythagorean Numerology is: 7

Examples of methylation in a Sentence

1. Daniel Belsky:

   This is not a game over moment. It’s more like game on, what we have now is a proof of concept — a methylation biomarker that shows faster aging in people we know to be at higher risk for disease, disability and death, and slower aging in people who we know to be at lower risk.

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References

1. ^ Wiktionary
   https://en.wiktionary.org/wiki/Methylation
2. ^ Wikipedia
   https://en.wikipedia.org/wiki/Methylation
3. ^ Wikidata
   https://www.wikidata.org/w/index.php?search=methylation