What does mepolizumab mean?
Definitions for mepolizumab
mepolizum·ab
This dictionary definitions page includes all the possible meanings, example usage and translations of the word mepolizumab.
Wiktionary
mepolizumabnoun
A humanized monoclonal antibody that recognizes interleukin-5 and is used to treat certain kinds of asthma and white blood cell diseases.
Wikipedia
Mepolizumab
Mepolizumab, sold under the brand name Nucala, is a humanized monoclonal antibody used for the treatment of severe eosinophilic asthma, eosinophilic granulomatosis, and hypereosinophilic syndrome (HES). It recognizes and blocks interleukin-5 (IL-5), a signalling protein of the immune system. The most common side effects include headache, injection site reactions, and back pain.
Wikidata
Mepolizumab
Mepolizumab is a humanized monoclonal antibody that recognizes interleukin-5, and is used to treat certain kinds of asthma and white blood cell diseases. Recent studies have concluded that mepolizumab may improve exacerbations in patients with severe eosinophilic asthma, an adult-onset asthma which represents less than 5% of all asthma. IL-5 is a chemical messenger in the immune system that stimulates the growth of eosinophils. In eosinophilic asthma, eosinophils are present in the lungs. When mepolizumab was given to people with eosinophilic asthma, it eliminated eosinophils from the bloodstream,and reduced eosinophils in the lungs and bone marrow. Mepolizumab also reduced the number of asthma exacerbations, and reduced the need for corticosteroids. Mepolizumab improved the quality of life, but the improvement was "not clinically meaningful," according to a reviewer. In a recent multi-centre, double-blinded, randomised, controlled trial study of Mepolizumab in severe eosinophilic asthma, Mepolizumab reduced the number of clinically significant exacerbations compared to a placebo. Additionally Mepolizumab reduced sputum and blood eosinophil counts and was shown to be safe for up to 12 months.
Numerology
Chaldean Numerology
The numerical value of mepolizumab in Chaldean Numerology is: 3
Pythagorean Numerology
The numerical value of mepolizumab in Pythagorean Numerology is: 7
Translations for mepolizumab
From our Multilingual Translation Dictionary
- mepolizumabulRomanian
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"mepolizumab." Definitions.net. STANDS4 LLC, 2024. Web. 26 Apr. 2024. <https://www.definitions.net/definition/mepolizumab>.
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