What does maximum tolerated dose mean?

Definitions for maximum tolerated dose
max·i·mum tol·er·at·ed dose

This dictionary definitions page includes all the possible meanings, example usage and translations of the word maximum tolerated dose.

Wikidata

  1. Maximum tolerated dose

    Maximum tolerated dose refers to the highest dose of a radiological or pharmacological treatment that will produce the desired effect without unacceptable toxicity. The purpose of administering MTD is to determine whether long-term exposure to a chemical might lead to unacceptable adverse health effects in a population, when the level of exposure is not sufficient to cause premature mortality due to short-term toxic effects. The maximum dose is used, rather than a lower dose, to reduce the number of test subjects, in order to detect an effect that might occur only rarely. This type of analysis is also used in establishing chemical residue tolerances in foods. Maximum tolerated dose studies are also done in clinical trials.

U.S. National Library of Medicine

  1. Maximum Tolerated Dose

    The highest dose of a biologically active agent given during a chronic study that will not reduce longevity from effects other than carcinogenicity. (from Lewis Dictionary of Toxicology, 1st ed)

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Numerology

  1. Chaldean Numerology

    The numerical value of maximum tolerated dose in Chaldean Numerology is: 7

  2. Pythagorean Numerology

    The numerical value of maximum tolerated dose in Pythagorean Numerology is: 3

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"maximum tolerated dose." Definitions.net. STANDS4 LLC, 2024. Web. 29 Apr. 2024. <https://www.definitions.net/definition/maximum+tolerated+dose>.

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