Definitions for lipoteichoic acid
lipote·i·choic acid

WiktionaryRate this definition:0.0 / 0 votes

1. lipoteichoic acidnoun

   Any of various lipid derivatives of teichoic acids

WikipediaRate this definition:0.0 / 0 votes

1. Lipoteichoic acid

   Lipoteichoic acid (LTA) is a major constituent of the cell wall of gram-positive bacteria. These organisms have an inner (or cytoplasmic) membrane and, external to it, a thick (up to 80 nanometer) peptidoglycan layer. The structure of LTA varies between the different species of Gram-positive bacteria and may contain long chains of ribitol or glycerol phosphate. LTA is anchored to the cell membrane via a diacylglycerol. It acts as regulator of autolytic wall enzymes (muramidases). It has antigenic properties being able to stimulate specific immune response.Lipoteichoic acid's chemical signals is C28H74O37P3=OH. LTA may bind to target cells non-specifically through membrane phospholipids, or specifically to CD14 and to Toll-like receptors. Binding to TLR-2 has shown to induce NF-κB expression(a central transcription factor), elevating expression of both pro- and anti-apoptotic genes. Its activation also induces mitogen-activated protein kinases (MAPK) activation along with phosphoinositide 3-kinase activation.

WikidataRate this definition:0.0 / 0 votes

1. Lipoteichoic acid

   Lipoteichoic acid is a major constituent of the cell wall of Gram-positive bacteria. These organisms have an inner membrane and, external to it, a thick peptidoglycan layer. The structure of LTA varies between the different species of Gram positive bacteria and may contain long chains of ribitol or glycerol phosphate. LTA is anchored to the cell membrane via a diacylglycerol. It acts as regulator of autolytic wall enzymes. It has antigenic properties being able to stimulate specific immune response and is released from the bacterial cells mainly after bacteriolysis induced by lysozyme, cationic peptides from leucocytes, or beta-lactam antibiotics. LTA may bind to target cells non-specifically through membrane phospholipids, or specifically to CD14 and to Toll-like receptors. Binding to TLR-2 has shown to induce NF-κB expression, elevating expression of both pro- and anti-apoptotic genes. Its activation also induces mitogen-activated protein kinases activation along with Phosphoinositide 3-kinase activation. LTA bound to targets can interact with circulating antibodies and activate the complement cascade to induce a passive immune kill phenomenon. It also triggers the release from neutrophils and macrophages of reactive oxygen and nitrogen species, acid hydrolases, highly cationic proteinases, bactericidal cationic peptides, growth factors, and cytotoxic cytokines, which may act in synergy to amplify cell damage. Therefore, LTA shares many pathogenic similarities with endotoxins.

How to pronounce lipoteichoic acid?

1. Alex

   US English

   David

   US English

   Mark

   US English

   Daniel

   British

   Libby

   British

   Mia

   British

   Karen

   Australian

   Hayley

   Australian

   Natasha

   Australian

   Veena

   Indian

   Priya

   Indian

   Neerja

   Indian

   Zira

   US English

   Oliver

   British

   Wendy

   British

   Fred

   US English

   Tessa

   South African

How to say lipoteichoic acid in sign language?

Numerology

1. Chaldean Numerology

   The numerical value of lipoteichoic acid in Chaldean Numerology is: 3

2. Pythagorean Numerology

   The numerical value of lipoteichoic acid in Pythagorean Numerology is: 6

References

1. ^ Wiktionary
   https://en.wiktionary.org/wiki/Lipoteichoic_Acid
2. ^ Wikipedia
   https://en.wikipedia.org/wiki/Lipoteichoic_Acid
3. ^ Wikidata
   https://www.wikidata.org/w/index.php?search=lipoteichoic acid