Definitions for ketamine
ke·tamine

Princeton's WordNetRate this definition:0.0 / 0 votes

1. ketamine, ketamine hydrochloride, Ketalarnoun

   a general anesthetic and tranquilizer (not a barbiturate) that is administered intravenously or intramuscularly; used mainly by veterinarians or for minor surgery with geriatric or pediatric patients; taken in large doses it causes hallucinations similar to those associated with the use of PCP

WiktionaryRate this definition:0.0 / 0 votes

1. ketaminenoun

   a pain-killing drug and anaesthetic

WikipediaRate this definition:0.0 / 0 votes

1. Ketamine

   Ketamine is a dissociative anesthetic used medically for induction and maintenance of anesthesia. It is also used as a recreational drug. Ketamine is also simple to administer and highly tolerable compared to drugs with similar effects which are flammable, irritating, or even explosive. Ketamine is a novel compound, derived from PCP, created in pursuit of a safer anesthetic with similar characteristics. Ketamine is also used for acute pain management.At anesthetic doses, ketamine induces a state of "dissociative anesthesia", a trance-like state providing pain relief, sedation, and amnesia. The distinguishing features of ketamine anesthesia are preserved breathing and airway reflexes, stimulated heart function with increased blood pressure, and moderate bronchodilation. At lower, sub-anesthetic doses, ketamine is a promising agent for pain and treatment-resistant depression. However, the antidepressant action of a single administration of ketamine wanes with time. The long-term effects of repeated use are largely unknown, and are an area of active investigation.Liver and urinary toxicity have been reported among regular users of high doses of ketamine for recreational purposes. Ketamine is an NMDA receptor pore blocker and that accounts for most of its actions except the antidepressive effect, the mechanism of which is a matter of much research and debate. Ketamine was first synthesized in 1962 and approved for use in the United States in 1970. It has been regularly used in veterinary medicine and was extensively used for surgical anaesthesia in the Vietnam War. When used as a recreational drug, it is found both in powder and liquid form, and is often referred to as "Special K" for its hallucinogenic and dissociative effects. Along with other psychotropic drugs, it is on the World Health Organization's List of Essential Medicines. It is available as a generic medication.

ChatGPTRate this definition:0.0 / 0 votes

1. ketamine

   Ketamine is a medication that is primarily used for the induction and maintenance of anesthesia. It can also be used for pain management and the treatment of depression. It works by blocking the neurotransmitter N-methyl-D-aspartate (NMDA) receptor in the brain, creating a trance-like state, pain relief, sedation, and memory loss. It is classified as a dissociative anesthetic and it can sometimes be used recreationally due to its hallucinogenic and dissociative effects.

WikidataRate this definition:0.0 / 0 votes

1. Ketamine

   Ketamine is a drug used in human and veterinary medicine, primarily for the induction and maintenance of general anesthesia, usually in combination with a sedative. Other uses include sedation in intensive care, analgesia, and treatment of bronchospasm. Ketamine has a wide range of effects in humans, including analgesia, anesthesia, hallucinations, elevated blood pressure, and bronchodilation. Like other drugs of its class such as tiletamine and phencyclidine, it induces a state referred to as "dissociative anesthesia" and is used as a recreational drug. Ketamine has been shown to be effective in treating depression in patients with bipolar disorder who have not responded to antidepressants. In persons with major depressive disorder, it produces a rapid antidepressant effect, acting within two hours as opposed to the several weeks taken by typical antidepressants to work. Its hydrochloride salt is sold as Ketanest, Ketaset, and Ketalar. Pharmacologically, ketamine is classified as an NMDA receptor antagonist. At high, fully anesthetic level doses, ketamine has also been found to bind to μ-opioid receptors type 2 in cultured human neuroblastoma cells – however, without agonist activity – and to sigma receptors in rats. Also, ketamine interacts with muscarinic receptors, descending monoaminergic pain pathways and voltage-gated calcium channels.

U.S. National Library of MedicineRate this definition:0.0 / 0 votes

1. Ketamine

   A cyclohexanone derivative used for induction of anesthesia. Its mechanism of action is not well understood, but ketamine can block NMDA receptors (RECEPTORS, N-METHYL-D-ASPARTATE) and may interact with sigma receptors.

Matched Categories

1. • Club Drug
   • General Anesthetic

How to pronounce ketamine?

1. Alex

   US English

   David

   US English

   Mark

   US English

   Daniel

   British

   Libby

   British

   Mia

   British

   Karen

   Australian

   Hayley

   Australian

   Natasha

   Australian

   Veena

   Indian

   Priya

   Indian

   Neerja

   Indian

   Zira

   US English

   Oliver

   British

   Wendy

   British

   Fred

   US English

   Tessa

   South African

How to say ketamine in sign language?

Numerology

1. Chaldean Numerology

   The numerical value of ketamine in Chaldean Numerology is: 9

2. Pythagorean Numerology

   The numerical value of ketamine in Pythagorean Numerology is: 6

Examples of ketamine in a Sentence

1. Walter Dunn .:

   Even clinicians would have a difficult time diagnosing an excited delirium, when you employ ketamine you better be darn sure that this is excited delirium and not something else.

2. Celia Morgan:

   Ketamine is a well-tolerated drug and can help alleviate the symptoms of depression, with a pilot study suggesting that it could cut alcohol relapse rates by more than half, this trial will allow us to examine whether ketamine, combined with therapy, can indeed help people stay abstinent from alcohol.

3. Kevin Kane:

   The ketamine may be a way to improve their mood and stop their suicidal thinking until the other antidepressants -- the more standard antidepressants -- have the six-week time window to work, ketamine may be just the thing that gets someone through that window until other medications get the chance to kick in.

4. Joseph Baker:

   The most powerful medication that we have on the ambulance is our ability to speak with patients. Ketamine takes that away. i don't believe it should be requested by police. I don't tell them when to use their mace. They should not tell me to administer drugs.

5. Kenneth Udoibok:

   People are not complaining that Joseph Baker injected them with ketamine. They are complaining that a police officer caused that to happen.

Popularity rank by frequency of use

References

1. ^ Princeton's WordNet
   http://wordnetweb.princeton.edu/perl/webwn?s=ketamine
2. ^ Wiktionary
   https://en.wiktionary.org/wiki/Ketamine
3. ^ Wikipedia
   https://en.wikipedia.org/wiki/Ketamine
4. ^ ChatGPT
   https://chat.openai.com
5. ^ Wikidata
   https://www.wikidata.org/w/index.php?search=ketamine