Definitions of immunophilins

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Definition of 'immunophilins'

U.S. National Library of Medicine

1. immunophilins
Members of a family of highly conserved proteins which are all cis-trans peptidyl-prolyl isomerases (PEPTIDYLPROLYL ISOMERASE). They bind the immunosuppressant drugs CYCLOSPORINE; TACROLIMUS and SIROLIMUS. They possess rotamase activity, which is inhibited by the immunosuppressant drugs that bind to them.

'immunophilins' - Nearby Entries
immunomagnetic separation immunomodulation immunophenotyping immunophilins immunoprecipitation immunoproliferative disorders immunoproliferative small intestinal disease

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