Definitions for idazoxan
This page provides all possible meanings and translations of the word idazoxan
Idazoxan is a drug which is used in scientific research. It acts as both a selective α2 adrenergic receptor antagonist, and an antagonist for the imidazoline receptor. Idazoxan has been under investigation as an antidepressant, but it did not reach the market as such. More recently, it is under investigation as an adjunctive treatment in schizophrenia. Due to its alpha-2 receptor antagonism it is capable of enhancing therapeutic effects of antipsychotics, possibly by enhancing dopamine neurotransmission in the prefrontal cortex of the brain, a brain area thought to be involved in the pathogenesis of schizophrenia.
U.S. National Library of Medicine
An alpha(2)-adrenoceptor antagonist. It has been used experimentally to test the binding activity of other chemicals.
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