Definitions for hyperkeratosisˌhaɪ pərˌkɛr əˈtoʊ sɪs

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  1. hyperkeratosis(Noun)

    Excess keratin formation on the skin surface, as can be seen in a number of dermatologic conditions.

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  1. Hyperkeratosis

    Hyperkeratosis is thickening of the stratum corneum, often associated with a qualitative abnormality of the keratin, and also usually accompanied by an increase in the granular layer. As the corneum layer normally varies greatly in thickness in different sites, some experience is needed to assess minor degrees of hyperkeratosis. It can be caused by vitamin A deficiency or chronic exposure to arsenic. It can be treated with urea-containing creams, which dissolve the intercellular matrix of the cells of the stratum corneum, promoting desquamation of scaly skin, eventually resulting in softening of hyperkeratotic areas.

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