What does grepafloxacin mean?
Definitions for grepafloxacin
grepafloxacin
This dictionary definitions page includes all the possible meanings, example usage and translations of the word grepafloxacin.
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Wiktionary
grepafloxacinnoun
An oral broad-spectrum quinoline antibacterial drug, no longer used because of cardiac side effects.
Wikidata
Grepafloxacin
Grepafloxacin hydrochloride was a oral broad-spectrum fluoroquinolone antibacterial agent used to treat bacterial infections. Grepafloxacin was withdrawn world wide from markets owing to its side effect of lengthening the QT interval on the electrocardiogram, leading to cardiac events and sudden death. GlaxoSmithKline marketed Raxar at doses of 200 milligrams, 400 milligrams and 600 milligrams. Records filed with the U.S. Food and Drug Administration showed that Raxar was cited as a suspect in the reported deaths of 13 patients. There were four deaths associated with patients who took Raxar in 600-milligram doses within the clinical trials submitted with the New Drug Application in 1997. The package insert approved by the FDA stated that "there were no deaths or permanent disabilities" among those who took Raxar in 400-milligram doses. It was the FDA’s position that none of the noted fatalities "was shown to be attributable to Raxar." On Oct. 27, 1999, GlaxoSmithKline removed Raxar from clinical use citing to the fact that Raxar's effect on "QT interval prolongation" was unacceptably risky. Other drugs within this class have also been associated with QT interval prolongation, resulting in sudden death of the patient.
Numerology
Chaldean Numerology
The numerical value of grepafloxacin in Chaldean Numerology is: 7
Pythagorean Numerology
The numerical value of grepafloxacin in Pythagorean Numerology is: 5
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"grepafloxacin." Definitions.net. STANDS4 LLC, 2024. Web. 26 Apr. 2024. <https://www.definitions.net/definition/grepafloxacin>.
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