What does gefitinib mean?
Definitions for gefitinib
gefi·tinib
This dictionary definitions page includes all the possible meanings, example usage and translations of the word gefitinib.
Wiktionary
gefitinibnoun
A drug, used in the treatment of certain types of cancer, that acts in a similar way to erlotinib by selectively targeting the mutant proteins in malignant cells.
Etymology: Unknown + -tinib
Wikipedia
Gefitinib
Gefitinib, sold under the brand name Iressa, is a medication used for certain breast, lung and other cancers. Gefitinib is an EGFR inhibitor, like erlotinib, which interrupts signaling through the epidermal growth factor receptor (EGFR) in target cells. Therefore, it is only effective in cancers with mutated and overactive EGFR, but resistances to gefitinib can arise through other mutations. It is marketed by AstraZeneca and Teva. It is on the World Health Organization's List of Essential Medicines. It is available as a generic medication.
Wikidata
Gefitinib
An anilinoquinazoline with antineoplastic activity. Gefitinib inhibits the catalytic activity of numerous tyrosine kinases including the epidermal growth factor receptor (EGFR), which may result in inhibition of tyrosine kinase-dependent tumor growth. Specifically, this agent competes with the binding of ATP to the tyrosine kinase domain of EGFR, thereby inhibiting receptor autophosphorylation and resulting in inhibition of signal transduction. Gefitinib may also induce cell cycle arrest and inhibit angiogenesis. (NCI04)
Numerology
Chaldean Numerology
The numerical value of gefitinib in Chaldean Numerology is: 3
Pythagorean Numerology
The numerical value of gefitinib in Pythagorean Numerology is: 9
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"gefitinib." Definitions.net. STANDS4 LLC, 2024. Web. 7 May 2024. <https://www.definitions.net/definition/gefitinib>.
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