Definitions for fostriecin

This page provides all possible meanings and translations of the word fostriecin

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  1. fostriecin(Noun)

    An antibiotic, obtained from Streptomyces bacteria, that has antitumor activity

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  1. Fostriecin

    An anti-tumor antibiotic isolated from the bacterium Streptomyces pulveraceus. Fostriecin inhibits topoisomerase II catalytic activity, resulting in protein-associated strand breaks and impaired DNA and RNA synthesis in various malignant cell types. This agent also inhibits serine/threonine protein phosphatase type 2A in some tumor cell types, thereby interfering with cellular proliferation and differentiation. (NCI04)

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