Definitions for fmrfamide
fmrfamide

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1. FMRFamide

   FMRFamide (H-Phe-Met-Arg-Phe-NH2) is a neuropeptide from a broad family of FMRFamide-related peptides (FaRPs) all sharing an -RFamide sequence at their C-terminus. First identified in Hard clam (Mercenaria mercenaria), it is thought to play an important role in cardiac activity regulation. Several FMRFamide related peptides are known, regulating various cellular functions and possessing pharmacological actions, such as anti-opiate effects. In Mercenaria mercenaria, FMRFamide has been isolated and demonstrated to increase both the force and frequency of the heartbeat through a biochemical pathway that is thought to involve the increase of cytoplasmic cAMP in the ventricular region.FMRFamide is an important neuropeptide in several phyla such as Insecta, Nematoda, Mollusca, and Annelida. It is the most abundant neuropeptide in endocrine cells of insect alimentary tracts along with allatostatin and tachykinin families, however the neuropeptide’s function is not known. Generally, the neuropeptide is encoded by several genes such as flp-1 through flp-22 in C. elegans. The common precursor of the FaRPs is modified to yield many different neuropeptides all having the same FMRFamide sequence. Moreover, these peptides are not functionally redundant.In invertebrates, the FMRFamide-related peptides are known to affect heart rate, blood pressure, gut motility, feeding behaviour and reproduction. In vertebrates such as mice, they are known to affect opioid receptors resulting in elicitation of naloxone-sensitive antinociception and reduction of morphine-induced antinociception.Detection of this neuropeptide is important because its expression lays down the foundation of the CNS in the early stages of development in invertebrates. In recent years, neuromodulatory actions of FMRFamide in invertebrates have become more apparent. This is, in part, due to the extensive studies done on the Planorbid and Lymnaeid families of pond snails.

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1. fmrfamide

   FMRFamide is a small peptide that acts as a neurotransmitter or neuromodulator in invertebrates and some vertebrates. It is associated with various physiological functions such as modulation of feeding behavior, reproduction, and stress response.

WikidataRate this definition:0.0 / 0 votes

1. FMRFamide

   FMRFamide is a neuropeptide from a broad family of FMRFamide-related peptides all sharing an -RFamide sequence at their C-terminus. First identified in Hard clam Mercenaria mercenaria it is thought to play an important role in cardiac activity regulation. Several FMRFamid related peptides are known, regulating various cellular functions and possessing pharmacological actions, such as anti-opiate effects. In Mercenaria mercenaria, FMRFamide has been isolated and demonstrated to increase both the force and frequency of the heartbeat through a biochemical pathway that is thought to involve the increase of cytoplasmic cAMP in the ventricular region. FMRFamide is an important neuropeptide in several phyla such as Insecta, Nematoda, Mollusca and Annelida. It is the most abundant neuropeptide in endocrine cells of insect alimentary tracts along with allatostatin and tachykinin families, however the neuropeptide’s function is not known. Generally, the neuropeptide is encoded by several genes such as flp-1 through flp-22 in C. elegans. The common precursor of the FaRPs is modified to yield many different neuropeptides all having the same FMRFamide sequence. Moreover, these peptides are not functionally redundant.

U.S. National Library of MedicineRate this definition:0.0 / 0 votes

1. FMRFamide

   A molluscan neuroactive peptide which induces a fast excitatory depolarizing response due to direct activation of amiloride-sensitive SODIUM CHANNELS. (From Nature 1995; 378(6558): 730-3)

How to pronounce fmrfamide?

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Numerology

1. Chaldean Numerology

   The numerical value of fmrfamide in Chaldean Numerology is: 1

2. Pythagorean Numerology

   The numerical value of fmrfamide in Pythagorean Numerology is: 3

References

1. ^ Wikipedia
   https://en.wikipedia.org/wiki/Fmrfamide
2. ^ ChatGPT
   https://chat.openai.com
3. ^ Wikidata
   https://www.wikidata.org/w/index.php?search=fmrfamide