What does exisulind mean?
Definitions for exisulind
ex·isulind
This dictionary definitions page includes all the possible meanings, example usage and translations of the word exisulind.
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Wiktionary
exisulindnoun
A particular drug used in chemotherapy.
Wikipedia
Exisulind
Exisulind (tentative trade name Aptosyn) is an antineoplastic agent. It acts by inhibiting the enzyme cyclic guanosine monophosphate phosphodiesterase type 5 (EC 3.1.4.17). It is the sulfone derivative of sulindac, an NSAID. Unlike sulindac, it has known effects on prostaglandin synthesis. It was developed as the potential treatment of several conditions including familial adenomatous polyposis (FAP), precancerous sporadic colonic polyps, cervical dysplasia and the prevention of tumor recurrence in prostate and breast cancer. Exisulind inhibits the enzyme cGMP-PDE, overexpressed in precancerous and cancerous colorectal cells, and induces apoptosis in such cells with minimal effects on normal cells. This apoptotic effect is independent of COX-1 or COX-2 inhibition, p53, Bcl-2, or cell cycle arrest. Preclinical evidence suggests that exisulind also inhibits angiogenesis.
Wikidata
Exisulind
Exisulind is a drug used to treat cancer. It acts by inhibiting the enzyme cyclic guanosine monophosphate phosphodiesterase. Trademark by OSI Pharmaceuticals is Aptosyn. NCBI PubChem ID 5472495. Also listed as Sulindac sulfone which is a metabolic product of Sulindac.
Numerology
Chaldean Numerology
The numerical value of exisulind in Chaldean Numerology is: 6
Pythagorean Numerology
The numerical value of exisulind in Pythagorean Numerology is: 9
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"exisulind." Definitions.net. STANDS4 LLC, 2024. Web. 19 Mar. 2024. <https://www.definitions.net/definition/exisulind>.
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