What does demecolcine mean?
Definitions for demecolcine
de·mecol·cine
This dictionary definitions page includes all the possible meanings, example usage and translations of the word demecolcine.
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Wiktionary
demecolcinenoun
A particular drug used in chemotherapy.
Wikipedia
Demecolcine
Demecolcine (INN; also known as colcemid) is a drug used in chemotherapy. It is closely related to the natural alkaloid colchicine with the replacement of the acetyl group on the amino moiety with methyl, but it is less toxic. It depolymerises microtubules and limits microtubule formation (inactivates spindle fibre formation), thus arresting cells in metaphase and allowing cell harvest and karyotyping to be performed. During cell division, demecolcine inhibits mitosis at metaphase by inhibiting spindle formation. Medically, demecolcine has been used to improve the results of cancer radiotherapy by synchronising tumour cells at metaphase, the radiosensitive stage of the cell cycle.In animal cloning procedures, demecolcine makes an ovum eject its nucleus, creating space for insertion of a new nucleus.
Wikidata
Demecolcine
Demecolcine, also known as colcemid, is a drug used in chemotherapy.It is closely related to the natural alkaloid colchicine with the replacement of the acetyl group on the amino moiety with methyl, but it is less toxic. It depolymerises microtubules and limits microtubule formation, thus arresting cells in metaphase and allowing cell harvest and karyotyping to be performed. During cell division Demecolcine inhibits mitosis at metaphase by inhibiting spindle formation. Medically Demecolcine has been used to improve the results of cancer radiotherapy by synchronising tumour cells at metaphase, the radiosensitive stage of the cell cycle. In animal cloning procedures Demecolcine makes an ovum eject its nucleus, creating space for insertion of a new nucleus.
U.S. National Library of Medicine
Demecolcine
An alkaloid isolated from Colchicum autumnale L. and used as an antineoplastic.
Numerology
Chaldean Numerology
The numerical value of demecolcine in Chaldean Numerology is: 9
Pythagorean Numerology
The numerical value of demecolcine in Pythagorean Numerology is: 7
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"demecolcine." Definitions.net. STANDS4 LLC, 2024. Web. 26 Apr. 2024. <https://www.definitions.net/definition/demecolcine>.
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