Definitions for dactinomycin
This page provides all possible meanings and translations of the word dactinomycin
A chromopeptide antineoplastic antibiotic isolated from the bacterium Streptomyces parvulus. Dactinomycin intercalates between adjacent guanine-cytosine base pairs, blocking the transcription of DNA by RNA polymerase; it also causes single-strand DNA breaks, possibly via a free-radical intermediate or an interaction with topoisomerase II. (NCI04)
U.S. National Library of Medicine
A compound composed of a two CYCLIC PEPTIDES attached to a phenoxazine that is derived from STREPTOMYCES parvullus. It binds to DNA and inhibits RNA synthesis (transcription), with chain elongation more sensitive than initiation, termination, or release. As a result of impaired mRNA production, protein synthesis also declines after dactinomycin therapy. (From AMA Drug Evaluations Annual, 1993, p2015)
The numerical value of dactinomycin in Chaldean Numerology is: 3
The numerical value of dactinomycin in Pythagorean Numerology is: 4
Images & Illustrations of dactinomycin
Find a translation for the dactinomycin definition in other languages:
Select another language:
Discuss these dactinomycin definitions with the community:
Word of the Day
Would you like us to send you a FREE new word definition delivered to your inbox daily?
Use the citation below to add this definition to your bibliography:
"dactinomycin." Definitions.net. STANDS4 LLC, 2016. Web. 27 Sep. 2016. <http://www.definitions.net/definition/dactinomycin>.