Definitions for cytokine storm
cy·tokine storm

WiktionaryRate this definition:5.0 / 1 vote

1. cytokine stormnoun

   An immune system - cytokine positive feedback reaction to certain infections. Suspected as being implicated in the high mortality rates of the Spanish flu outbreak of 1918-1920.

WikipediaRate this definition:0.0 / 0 votes

1. Cytokine storm

   A cytokine storm, also called hypercytokinemia, is a physiological reaction in humans and other animals in which the innate immune system causes an uncontrolled and excessive release of pro-inflammatory signaling molecules called cytokines. Normally, cytokines are part of the body's immune response to infection, but their sudden release in large quantities can cause multisystem organ failure and death.Cytokine storms can be caused by a number of infectious and non-infectious etiologies, especially viral respiratory infections such as H1N1 influenza, H5N1 influenza, SARS-CoV-1, and SARS-CoV-2, Influenza B, Parainfluenza virus. Other causative agents include the Epstein-Barr virus, cytomegalovirus, group A streptococcus, and non-infectious conditions such as graft-versus-host disease. The viruses can invade lung epithelial cells and alveolar macrophages to produce viral nucleic acid, which stimulates the infected cells to release cytokines and chemokines, activating macrophages, dendritic cells, and others.Cytokine storm syndrome is a diverse set of conditions that can result in a cytokine storm. Cytokine storm syndromes include familial hemophagocytic lymphohistiocytosis, Epstein-Barr virus–associated hemophagocytic lymphohistiocytosis, systemic or non-systemic juvenile idiopathic arthritis–associated macrophage activation syndrome, NLRC4 macrophage activation syndrome, cytokine release syndrome and sepsis.

WikidataRate this definition:1.0 / 1 vote

1. Cytokine storm

   A cytokine storm, also known as cytokine cascade and hypercytokinemia is a potentially fatal immune reaction consisting of a positive feedback loop between cytokines and immune cells, with highly elevated levels of various cytokines.

How to pronounce cytokine storm?

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How to say cytokine storm in sign language?

Numerology

1. Chaldean Numerology

   The numerical value of cytokine storm in Chaldean Numerology is: 3

2. Pythagorean Numerology

   The numerical value of cytokine storm in Pythagorean Numerology is: 7

Examples of cytokine storm in a Sentence

1. Jonathan Reiner:

   And that was really the story of the pandemic in 1918 -- the flu pandemic. We had a U-shaped curve. It was the young and the old dying for different reasons, but the reason the young died was because they had a vigorous immune response -- the so-called cytokine storm, where your body makes immunological proteins that actually cause harm.

2. Vander Heide:

   One of the things people are seeing with Covid now is the cytokine storm that is generated by the virus.

3. Majid Fotuhi:

   There are people who have a measured response to the virus and their immune system can manage it without overreacting, healthy people who are asymptomatic are the ones who had just enough immune response to destroy the virus without creating a cytokine storm or blood clots.

4. Jonathan Reiner:

   We've certainly seen people come into our hospital, very young people( in their early 20s)... need to be put on ECMO, which is basically a heart-lung machine, for days or even weeks because they come in with cardiomyopathy, which is a response to a cytokine storm.

References

1. ^ Wiktionary
   https://en.wiktionary.org/wiki/Cytokine_Storm
2. ^ Wikipedia
   https://en.wikipedia.org/wiki/Cytokine_Storm
3. ^ Wikidata
   https://www.wikidata.org/w/index.php?search=cytokine storm