What does cyp17a1 mean?

Definitions for cyp17a1
cyp17a1

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Wikipedia

  1. CYP17A1

    Cytochrome P450 17A1 (steroid 17α-monooxygenase, 17α-hydroxylase, 17-alpha-hydroxylase, 17,20-lyase, 17,20-desmolase) is an enzyme of the hydroxylase type that in humans is encoded by the CYP17A1 gene on chromosome 10. It is ubiquitously expressed in many tissues and cell types, including the zona reticularis and zona fasciculata of the adrenal cortex as well as gonadal tissues. It has both 17α-hydroxylase and 17,20-lyase activities, and is a key enzyme in the steroidogenic pathway that produces progestins, mineralocorticoids, glucocorticoids, androgens, and estrogens. More specifically, the enzyme acts upon pregnenolone and progesterone to add a hydroxyl (-OH) group at carbon 17 position (C17) of the steroid D ring (the 17α-hydroxylase activity, EC 1.14.14.19), or acts upon 17α-hydroxyprogesterone and 17α-hydroxypregnenolone to split the side-chain off the steroid nucleus (the 17,20-lyase activity, EC 1.14.14.32).

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Numerology

  1. Chaldean Numerology

    The numerical value of cyp17a1 in Chaldean Numerology is: 4

  2. Pythagorean Numerology

    The numerical value of cyp17a1 in Pythagorean Numerology is: 9

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"cyp17a1." Definitions.net. STANDS4 LLC, 2024. Web. 2 May 2024. <https://www.definitions.net/definition/cyp17a1>.

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