Definitions for calpain

This page provides all possible meanings and translations of the word calpain

Wiktionary

  1. calpain(Noun)

    Any of a family of enzymes that regulate calcium in the body

Freebase

  1. Calpain

    A calpain is a protein belonging to the family of calcium-dependent, non-lysosomal cysteine proteases expressed ubiquitously in mammals and many other organisms. Calpains constitute the C2 family of protease clan CA in the MEROPS database. The calpain proteolytic system includes the calpain proteases, the small regulatory subunit CAPNS1, also known as CAPN4, and the endogenous calpain-specific inhibitor, calpastatin.

U.S. National Library of Medicine

  1. Calpain

    Cysteine proteinase found in many tissues. Hydrolyzes a variety of endogenous proteins including NEUROPEPTIDES; CYTOSKELETAL PROTEINS; proteins from SMOOTH MUSCLE; CARDIAC MUSCLE; liver; platelets; and erythrocytes. Two subclasses having high and low calcium sensitivity are known. Removes Z-discs and M-lines from myofibrils. Activates phosphorylase kinase and cyclic nucleotide-independent protein kinase. This enzyme was formerly listed as EC 3.4.22.4.

Translation

Find a translation for the calpain definition in other languages:

Select another language:

Discuss these calpain definitions with the community:


Citation

Use the citation below to add this definition to your bibliography:

Style:MLAChicagoAPA

"calpain." Definitions.net. STANDS4 LLC, 2014. Web. 25 Nov. 2014. <http://www.definitions.net/definition/calpain>.

Are we missing a good definition for calpain?


The Web's Largest Resource for

Definitions & Translations


A Member Of The STANDS4 Network


Nearby & related entries:

Alternative searches for calpain: