Definitions for auxotrophy
aux·otro·phy

WiktionaryRate this definition:0.0 / 0 votes

1. auxotrophynoun

   The inability of a microorganism to synthesize an organic compound required for its growth, often as a result of mutation

WikipediaRate this definition:0.0 / 0 votes

1. Auxotrophy

   Auxotrophy (Ancient Greek: αὐξάνω "to increase"; τροφή "nourishment") is the inability of an organism to synthesize a particular organic compound required for its growth (as defined by IUPAC). An auxotroph is an organism that displays this characteristic; auxotrophic is the corresponding adjective. Auxotrophy is the opposite of prototrophy, which is characterized by the ability to synthesize all the compounds needed for growth. Prototrophic cells (also referred to as the 'wild type') are self sufficient producers of all required metabolites (e.g. amino acids, lipids, cofactors), while auxotrophs require to be on medium with the metabolite that they cannot produce. For example saying a cell is methionine auxotrophic means that it would need to be on a medium containing methionine or else it would not be able to replicate. In this example this is because it is unable to produce its own methionine (methionine auxotroph). However, a prototroph or a methionine prototrophic cell would be able to function and replicate on a medium with or without methionine.Replica plating is a technique that transfers colonies from one plate to another in the same spot as the last plate so the different media plates can be compared side by side. It is used to compare the growth of the same colonies on different plates of media to determine which environments the bacterial colony can or cannot grow in (this gives insight to possible auxotrophic characteristics. The method of replica plating implemented by Joshua Lederberg and Esther Lederberg included auxotrophs that were temperature-sensitive; that is, their ability to synthesize was temperature-dependent. (Auxotrophs are usually not temperature-dependent. They can also depend on other factors.) It is also possible that an organism is auxotrophic to more than just one organic compound that it requires for growth.

WikidataRate this definition:0.0 / 0 votes

1. Auxotrophy

   Auxotrophy is the inability of an organism to synthesize a particular organic compound required for its growth. An auxotroph is an organism that displays this characteristic; auxotrophic is the corresponding adjective. Auxotrophy is the opposite of prototrophy, which is characterized by the ability to synthesize all the compounds needed for growth. The method of replica plating implemented by Esther Lederberg included auxotrophs that were temperature-sensitive; that is, their ability to synthesize was temperature-dependent. Multiple auxotrophs can also coexist at the same time, within the same organism. In genetics, a strain is said to be auxotrophic if it carries a mutation that renders it unable to synthesize an essential compound. For example, a yeast mutant with an inactivated uracil synthesis pathway gene is a uracil auxotroph. Such a strain is unable to synthesize uracil and will only be able to grow if uracil can be taken up from the environment. This is the opposite of a uracil prototroph, or in this case a wild-type strain, which can still grow in the absence of uracil. Auxotrophic genetic markers are often used in molecular genetics; they were famously used in Beadle and Tatum's Nobel prize-winning work on the one gene-one enzyme hypothesis.

How to pronounce auxotrophy?

1. Alex

   US English

   David

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   Mark

   US English

   Daniel

   British

   Libby

   British

   Mia

   British

   Karen

   Australian

   Hayley

   Australian

   Natasha

   Australian

   Veena

   Indian

   Priya

   Indian

   Neerja

   Indian

   Zira

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   Oliver

   British

   Wendy

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   Fred

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   Tessa

   South African

How to say auxotrophy in sign language?

Numerology

1. Chaldean Numerology

   The numerical value of auxotrophy in Chaldean Numerology is: 1

2. Pythagorean Numerology

   The numerical value of auxotrophy in Pythagorean Numerology is: 1

References

1. ^ Wiktionary
   https://en.wiktionary.org/wiki/Auxotrophy
2. ^ Wikipedia
   https://en.wikipedia.org/wiki/Auxotrophy
3. ^ Wikidata
   https://www.wikidata.org/w/index.php?search=auxotrophy