Definitions for amyloidosis
amy·loi·do·sis

Princeton's WordNetRate this definition:0.0 / 0 votes

1. amyloidosisnoun

   a disorder characterized by deposit of amyloid in organs or tissues; often secondary to chronic rheumatoid arthritis or tuberculosis or multiple myeloma

WiktionaryRate this definition:0.0 / 0 votes

1. amyloidosisnoun

   Any of a group of disorders in which the fibrous protein amyloid is deposited in an organ of the body.

WikipediaRate this definition:0.0 / 0 votes

1. Amyloidosis

   Amyloidosis is a group of diseases in which abnormal proteins, known as amyloid fibrils, build up in tissue. There are several non-specific and vague signs and symptoms associated with amyloidosis. These include fatigue, peripheral edema, weight loss, shortness of breath, palpitations, and feeling faint with standing. In AL amyloidosis, specific indicators can include enlargement of the tongue and periorbital purpura. In wild-type ATTR amyloidosis, non-cardiac symptoms include: bilateral carpal tunnel syndrome, lumbar spinal stenosis, biceps tendon rupture, small fiber neuropathy, and autonomic dysfunction.There are about 36 different types of amyloidosis, each due to a specific protein misfolding. Within these 36 proteins, 19 are grouped into localized forms, 14 are grouped as systemic forms, and 3 proteins can identify as either. These proteins can become irregular due to genetic effects, as well as through acquired environmental factors. The four most common types of systemic amyloidosis are light chain (AL), inflammation (AA), dialysis-related (Aβ2M), and hereditary and old age (ATTR and Wild-type transthyretin amyloid).Diagnosis may be suspected when protein is found in the urine, organ enlargement is present, or problems are found with multiple peripheral nerves and it is unclear why. Diagnosis is confirmed by tissue biopsy. Due to the variable presentation, a diagnosis can often take some time to reach.Treatment is geared towards decreasing the amount of the involved protein. This may sometimes be achieved by determining and treating the underlying cause. AL amyloidosis occurs in about 3–13 per million people per year and AA amyloidosis in about 2 per million people per year. The usual age of onset of these two types is 55 to 60 years old. Without treatment, life expectancy is between six months and four years. In the developed world about 1 per 1,000 people die annually from systemic amyloidosis. Amyloidosis has been described since at least 1639.

WikidataRate this definition:0.0 / 0 votes

1. Amyloidosis

   In medicine, amyloidosis refers to a variety of conditions wherein normally soluble proteins become insoluble and are deposited in the extracellular space of various organs or tissues, disrupting normal function. The insoluble fibrous protein aggregates that develop in amyloidosis are known as amyloids. They result from a change in the protein's secondary structure, which causes the protein to take on a particular aggregated insoluble form, similar to the beta-pleated sheet. Symptoms vary widely depending upon where in the body amyloid deposits accumulate. Amyloidosis may be inherited or acquired. Senile systemic amyloidosis was determined to be the primary cause of death for 70% of supercentenarians who have been autopsied.

U.S. National Library of MedicineRate this definition:0.0 / 0 votes

1. Amyloidosis

   A group of sporadic, familial and/or inherited, degenerative, and infectious disease processes, linked by the common theme of abnormal protein folding and deposition of AMYLOID. As the amyloid deposits enlarge they displace normal tissue structures, causing disruption of function. Various signs and symptoms depend on the location and size of the deposits.

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1. • Illness

How to pronounce amyloidosis?

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Numerology

1. Chaldean Numerology

   The numerical value of amyloidosis in Chaldean Numerology is: 8

2. Pythagorean Numerology

   The numerical value of amyloidosis in Pythagorean Numerology is: 6

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References

1. ^ Princeton's WordNet
   http://wordnetweb.princeton.edu/perl/webwn?s=amyloidosis
2. ^ Wiktionary
   https://en.wiktionary.org/wiki/Amyloidosis
3. ^ Wikipedia
   https://en.wikipedia.org/wiki/Amyloidosis
4. ^ Wikidata
   https://www.wikidata.org/w/index.php?search=amyloidosis