What does amyloid mean?
Definitions for amyloid
ˈæm əˌlɔɪdamy·loid
This dictionary definitions page includes all the possible meanings, example usage and translations of the word amyloid.
Princeton's WordNet
amyloidnoun
a non-nitrogenous food substance consisting chiefly of starch; any substance resembling starch
amyloidadjective
(pathology) a waxy translucent complex protein resembling starch that results from degeneration of tissue
starchlike, amylaceous, amyloid, amyloidal, farinaceousadjective
resembling starch
Wiktionary
amyloidnoun
A waxy compound of protein and polysaccharides that is found deposited in tissues in amyloidosis.
amyloidnoun
Any of various starchlike substances.
amyloidadjective
Containing or resembling starch
amyloidadjective
Applied to a mushroom that turns blue-black upon application of Melzer's reagent.
Wikipedia
Amyloid
Amyloids are aggregates of proteins characterised by a fibrillar morphology of typically 7–13 nm in diameter, a beta sheet (β-sheet) secondary structure (known as cross-β) and ability to be stained by particular dyes, such as Congo red. In the human body, amyloids have been linked to the development of various diseases. Pathogenic amyloids form when previously healthy proteins lose their normal structure and physiological functions (misfolding) and form fibrous deposits within and around cells. These protein misfolding and deposition processes disrupt the healthy function of tissues and organs. Such amyloids have been associated with (but not necessarily as the cause of) more than 50 human diseases, known as amyloidosis, and may play a role in some neurodegenerative diseases. Some of these diseases are mainly sporadic and only a few cases are familial. Others are only familial. Some are iatrogenic as they result from medical treatment. Prions are an infectious form of amyloids that can act as a template to convert other non-infectious forms. Amyloids may also have normal biological functions; for example, in the formation of fimbriae in some genera of bacteria, transmission of epigenetic traits in fungi, as well as pigment deposition and hormone release in humans.Amyloids have been known to arise from many different proteins. These polypeptide chains generally form β-sheet structures that aggregate into long fibers; however, identical polypeptides can fold into multiple distinct amyloid conformations. The diversity of the conformations may have led to different forms of the prion diseases.An unusual secondary structure named alpha sheet has been proposed as the toxic constituent of amyloid precursor proteins, but this idea is not widely accepted at present.
ChatGPT
amyloid
Amyloid refers to an abnormal protein substance that is deposited in various organs and tissues in the body due to certain diseases. These deposits can lead to damage and are typically associated with conditions such as Alzheimer's disease, Parkinson's disease, and several types of systemic amyloidosis. The structure of amyloid proteins is highly stable and resistant to proteolysis, complicating their removal from tissues.
Webster Dictionary
Amyloidadjective
alt. of Amyloidal
Amyloidnoun
a non-nitrogenous starchy food; a starchlike substance
Amyloidnoun
the substance deposited in the organs in amyloid degeneration
Wikidata
Amyloid
Amyloids are insoluble fibrous protein aggregates sharing specific structural traits. They arise from at least 18 inappropriately folded versions of proteins and polypeptides present naturally in the body. These misfolded structures alter their proper configuration such that they erroneously interact with one another or other cell components forming insoluble fibrils. They have been associated with the pathology of more than 20 serious human diseases in that, abnormal accumulation of amyloid fibrils in organs may lead to amyloidosis, and may play a role in various neurodegenerative disorders.
Chambers 20th Century Dictionary
Amyloid
am′i-loid, n. a half-gelatinous substance like starch, found in some seeds.—adj. Amyloid′al. [Gr. amylon, the finest flour, starch; lit. 'unground'—a, neg., mylē, a mill, and eidos, form.]
U.S. National Library of Medicine
Amyloid
A type of extracellularly deposited substance composed of an amyloid protein and additional components including HEPARAN SULFATE PROTEOGLYCAN; LAMININ; COLLAGEN TYPE IV; SERUM AMYLOID P-COMPONENT; and APOLIPOPROTEINS E which together form characteristic amyloid fibrils. The core of amyloid fibrils is formed by the stacking of overlapping beta-pleated sheet domains of the amyloid protein. There are many different amyloid proteins that have been found forming the core of the fibrils in vivo. However, amyloid can be formed from any protein that exposes beta-pleated strand conformations during unfolding or refolding. A common characteristic of amyloid is the ability to bind such dyes as CONGO RED and thioflavine.
Editors Contribution
amyloid
A form of protein.
Amyloid is found in seeds and within the human body.
Submitted by MaryC on December 26, 2020
Matched Categories
Numerology
Chaldean Numerology
The numerical value of amyloid in Chaldean Numerology is: 3
Pythagorean Numerology
The numerical value of amyloid in Pythagorean Numerology is: 7
Examples of amyloid in a Sentence
Although a very interesting paper, I don't think we need to worry excessively, this form of( human growth hormone) treatment stopped 20 years ago and there is no evidence from this paper or any other work I am aware of that any other form of treatment would result in exposure to amyloid.
Increasingly, there are imaging technologies that allow you to look at deposited amyloid plaque and even deposited tau in the brain.
Most of the associations we saw between menopause and tau protein occurred in the context of high amyloid, now a large portion of the older population do accumulate amyloid as they get older — it’s not that uncommon.
Marc actually tried out for aducanumab [trials] twice but he flunked because he did too well on his memory tests, we knew he had Alzheimer’s and he was building up amyloid plaques in the brain and had an increased genetic risk for Alzheimer’s.
They were able to develop imaging technology so you can actually look at a beta amyloid in an entire mouse brain and substantial chunks of human brain and study where is it located, what kind of cells is it connected with.
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Translations for amyloid
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"amyloid." Definitions.net. STANDS4 LLC, 2024. Web. 26 Apr. 2024. <https://www.definitions.net/definition/amyloid>.
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