What does Megalencephaly mean?
Definitions for Megalencephaly
mega·len·cepha·ly
This dictionary definitions page includes all the possible meanings, example usage and translations of the word Megalencephaly.
Wikipedia
Megalencephaly
Megalencephaly (or macrencephaly; abbreviated MEG) is a growth development disorder in which the brain is abnormally large. It is characterized by a brain with an average weight that is 2.5 standard deviations above the mean of the general population. Approximately 1 out of 50 children (2%) are said to have the characteristics of megalencephaly in the general population.A mutation in the PI3K-AKT pathway is believed to be the primary cause of brain proliferation and ultimately the root cause of megalencephaly. This mutation has produced a classification of brain overdevelopment that consists of two syndromes including megalencephaly-capillary malformation (MCAP) and megalencephaly-polydactyly-polymicrogyria-hydrocephalus (MPPH). Megalencephaly is usually diagnosed at birth and is confirmed with an MRI. There are several neuropsychiatric disorders linked with megalencephaly; however, studies have shown that autism is the most prevalent association with the malformation of MEG. Although no treatment currently exists for megalencephaly, management methods are focused at reducing deficits linked with autism. Most recent research is targeted at creating inhibitors to reduce the mutational pathway that causes megalencephaly.
Wikidata
Megalencephaly
Megalencephaly is a growth development disorder in which the brain is abnormally large. It is characterized by a brain with an average weight that is 2.5 standard deviations from the mean of the general population. Megalencephaly is usually diagnosed at birth and is confirmed with an MRI. A mutation in the PI3K-AKT pathway is believed to be the primary cause of brain proliferation and ultimately the root cause of megalencephaly. This mutation has produced a classification of brain overdevelopment that consists of two syndromes including, megalencephaly-capillary malformation and megalencephaly-polydactyly-polymicrogyria-hydrocephalus. Approximately 1 out of 50 children are said to have the characteristics of megalencephaly in the general population. There are several neuropsychiatric disorders linked with megalencephaly, however, studies have shown that autism is the most prevalent association with the malformation of MEG. Although no treatment currently exists for megalencephaly, management methods are focused at reducing deficits linked with autism. Most recent research is targeted at creating inhibitors to reduce the mutational pathway that causes megalencephaly.
Numerology
Chaldean Numerology
The numerical value of Megalencephaly in Chaldean Numerology is: 7
Pythagorean Numerology
The numerical value of Megalencephaly in Pythagorean Numerology is: 1
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"Megalencephaly." Definitions.net. STANDS4 LLC, 2024. Web. 4 May 2024. <https://www.definitions.net/definition/Megalencephaly>.
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