Definitions for Antibody
ˈæn tɪˌbɒd ian·ti·body

Princeton's WordNetRate this definition:0.0 / 0 votes

1. antibodynoun

   any of a large variety of proteins normally present in the body or produced in response to an antigen which it neutralizes, thus producing an immune response

GCIDERate this definition:0.0 / 0 votes

1. Antibodynoun

   (Med., Physiol. Chem.) Any of various bodies or substances in the blood which act in antagonism to harmful foreign bodies, as toxins or the bacteria producing the toxins. Normal blood serum apparently contains various antibodies, and the introduction of toxins or of foreign cells also stimulates production of their specific antibodies by the immune system. In certain

WiktionaryRate this definition:0.0 / 0 votes

1. antibodynoun

   A protein produced by B-lymphocytes that binds to a specific antigen.

2. Etymology: a calque of Antikörper.

WikipediaRate this definition:0.0 / 0 votes

1. Antibody

   An antibody (Ab), also known as an immunoglobulin (Ig), is a large, Y-shaped protein used by the immune system to identify and neutralize foreign objects such as pathogenic bacteria and viruses. The antibody recognizes a unique molecule of the pathogen, called an antigen. Each tip of the "Y" of an antibody contains a paratope (analogous to a lock) that is specific for one particular epitope (analogous to a key) on an antigen, allowing these two structures to bind together with precision. Using this binding mechanism, an antibody can tag a microbe or an infected cell for attack by other parts of the immune system, or can neutralize it directly (for example, by blocking a part of a virus that is essential for its invasion). To allow the immune system to recognize millions of different antigens, the antigen-binding sites at both tips of the antibody come in an equally wide variety. In contrast, the remainder of the antibody is relatively constant. It only occurs in a few variants, which define the antibody's class or isotype: IgA, IgD, IgE, IgG, and IgM. The constant region at the trunk of the antibody includes sites involved in interactions with other components of the immune system. The class hence determines the function triggered by an antibody after binding to an antigen, in addition to some structural features. Antibodies from different classes also differ in where they are released in the body and at what stage of an immune response. Together with B and T cells, antibodies comprise the most important part of the adaptive immune system. They occur in two forms: one that is attached to a B cell, and the other, a soluble form, that is unattached and found in extracellular fluids such as blood plasma. Initially, all antibodies are of the first form, attached to the surface of a B cell – these are then referred to as B-cell receptors (BCR). After an antigen binds to a BCR, the B cell activates to proliferate and differentiate into either plasma cells, which secrete soluble antibodies with the same paratope, or memory B cells, which survive in the body to enable long-lasting immunity to the antigen. Soluble antibodies are released into the blood and tissue fluids, as well as many secretions. Because these fluids were traditionally known as humors, antibody-mediated immunity is sometimes known as, or considered a part of, humoral immunity. The soluble Y-shaped units can occur individually as monomers, or in complexes of two to five units. Antibodies are glycoproteins belonging to the immunoglobulin superfamily. The terms antibody and immunoglobulin are often used interchangeably, though the term 'antibody' is sometimes reserved for the secreted, soluble form, i.e. excluding B-cell receptors.

ChatGPTRate this definition:0.0 / 0 votes

1. antibody

   An antibody is a large, Y-shaped protein produced by the immune system to identify and neutralize harmful substances such as bacteria, viruses, and other foreign substances. Also known as immunoglobulins, antibodies are secreted by immune cells called B lymphocytes and can recognize and bind specifically to unique molecules called antigens on the surface of these pathogens, marking them for destruction by other immune cells.

WikidataRate this definition:0.0 / 0 votes

1. Antibody

   An antibody, also known as an immunoglobulin, is a large Y-shaped protein produced by B-cells that is used by the immune system to identify and neutralize foreign objects such as bacteria and viruses. The antibody recognizes a unique part of the foreign target, called an antigen. Each tip of the "Y" of an antibody contains a paratope that is specific for one particular epitope on an antigen, allowing these two structures to bind together with precision. Using this binding mechanism, an antibody can tag a microbe or an infected cell for attack by other parts of the immune system, or can neutralize its target directly. The production of antibodies is the main function of the humoral immune system. Antibodies are secreted by a type of white blood cell called a plasma cell. Antibodies can occur in two physical forms, a soluble form that is secreted from the cell, and a membrane-bound form that is attached to the surface of a B cell and is referred to as the B cell receptor. The BCR is only found on the surface of B cells and facilitates the activation of these cells and their subsequent differentiation into either antibody factories called plasma cells, or memory B cells that will survive in the body and remember that same antigen so the B cells can respond faster upon future exposure. In most cases, interaction of the B cell with a T helper cell is necessary to produce full activation of the B cell and, therefore, antibody generation following antigen binding. Soluble antibodies are released into the blood and tissue fluids, as well as many secretions to continue to survey for invading microorganisms.

Matched Categories

1. • Protein

British National Corpus

1. Nouns Frequency

   Rank popularity for the word 'Antibody' in Nouns Frequency: #2239

How to pronounce Antibody?

1. Alex

   US English

   David

   US English

   Mark

   US English

   Daniel

   British

   Libby

   British

   Mia

   British

   Karen

   Australian

   Hayley

   Australian

   Natasha

   Australian

   Veena

   Indian

   Priya

   Indian

   Neerja

   Indian

   Zira

   US English

   Oliver

   British

   Wendy

   British

   Fred

   US English

   Tessa

   South African

How to say Antibody in sign language?

Numerology

1. Chaldean Numerology

   The numerical value of Antibody in Chaldean Numerology is: 7

2. Pythagorean Numerology

   The numerical value of Antibody in Pythagorean Numerology is: 9

Examples of Antibody in a Sentence

1. Jeremy Farrar:

   It is impossible to overstate the implications of this work in all Sir Gregory P. Winter daily lives -- biofuels, chemicals, environment, medicine and so much more e.g. treatment of cancer, arthritis, Crohn's, UC and infections -- there are patients with Ebola being treated today with antibody therapies, this has impacted so much of modern medicine.

2. George Yancopoulos:

   We use thisto produce some of the mostimportant and safest medicinesin the world right now, to fightblindness, asthma, cancer, atopic dermatitis, heart diseaseand most importantly, we used this to produce the firsttherapeutic that will beapproved by the FDA for Ebola, and sowe made an antibody cocktailspecific for ebola. It wastested in a study coordinated bythe World Health Organizationand the NIH.

3. Scott Gottlieb:

   We’re going to have to update our vaccines and our antibody drugs and other therapeutics regularly to keep up with these new variants as they emerge.

4. Gail Demmler:

   I also personally recommend that every woman know her CMV status and ask her OB-GYN for a test, if she is antibody negative at beginning of pregnancy, she will know that she is very vulnerable.

5. Wang Fusheng:

   COVID vaccines do not cause leukemia or diabetes, nor do they affect genetic development, cause tumor metastasis or antibody-dependent enhancement, and those are irresponsible, false information on the internet.

Popularity rank by frequency of use

References

1. ^ Princeton's WordNet
   http://wordnetweb.princeton.edu/perl/webwn?s=Antibody
2. ^ GCIDE
   https://gcide.gnu.org.ua/?q=Antibody
3. ^ Wiktionary
   https://en.wiktionary.org/wiki/Antibody
4. ^ Wikipedia
   https://en.wikipedia.org/wiki/Antibody
5. ^ ChatGPT
   https://chat.openai.com
6. ^ Wikidata
   https://www.wikidata.org/w/index.php?search=Antibody