Definitions for 5-methylcytosine

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  1. 5-Methylcytosine

    5-Methylcytosine is a methylated form of the DNA base cytosine that may be involved in the regulation of gene transcription. When cytosine is methylated, the DNA maintains the same sequence, but the expression of methylated genes can be altered. 5-Methylcytosine is incorporated in the nucleoside 5-methylcytidine. In 5-methylcytosine, a methyl group, is attached to the 5th atom in the 6-atom ring. This methyl group distinguishes 5-methylcytosine from cytosine.

U.S. National Library of MedicineRate this definition:(0.00 / 0 votes)

  1. 5-Methylcytosine

    A methylated nucleotide base found in eukaryotic DNA. In ANIMALS, the DNA METHYLATION of CYTOSINE to form 5-methylcytosine is found primarily in the palindromic sequence CpG. In PLANTS, the methylated sequence is CpNpGp, where N can be any base.

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