cardiac glycoside, cardiac glucoside(noun)
obtained from a number of plants and used to stimulate the heart in cases of heart failure
Cardiac glycosides are a class of organic compounds that increase the output force of the heart and decrease its rate of contractions by inhibiting the cellular sodium-potassium ATPase pump. Their beneficial medical uses are as treatments for congestive heart failure and cardiac arrhythmias; however, their relative toxicity prevents them from being widely used. Most commonly found as secondary metabolites in several plants such as foxglove plants, these compounds nevertheless have a diverse range of biochemical effects regarding cardiac cell function and have also been suggested for use in cancer treatment.
Cardiac glucoside is a type of compound commonly found in several plant species. It has the ability to enhance the function of the heart muscle contractions, influencing the heart's rhythm and rate. The compound chiefly inhibits the enzyme activity of Na+/K+ -ATPase, leading to an increased concentration of intracellular calcium in the cardiac cells, thus improving cardiac output. Examples of such substances include digoxin and ouabain. Despite beneficial effects, excessive intake can cause toxicity.
The numerical value of cardiac glucoside in Chaldean Numerology is: 5
The numerical value of cardiac glucoside in Pythagorean Numerology is: 8