What does zona fasciculata mean?
Definitions for zona fasciculata
zon·a fas·ci·c·u·la·ta
This dictionary definitions page includes all the possible meanings, example usage and translations of the word zona fasciculata.
Wikipedia
Zona fasciculata
The zona fasciculata (sometimes, fascicular or fasciculate zone) constitutes the middle and also the widest zone of the adrenal cortex, sitting directly beneath the zona glomerulosa. Constituent cells are organized into bundles or "fascicles". The zona fasciculata chiefly produces glucocorticoids (mainly cortisol in humans), which regulate the metabolism of glucose. Glucocorticoid production is stimulated by adrenocorticotropic hormone (ACTH), which is released from the anterior pituitary, especially in times of stress as part of the fight-or-flight response. The zona fasciculata also generates a small amount of weak androgens (e.g., dehydroepiandrosterone). The main source of androgens will come from the zona reticularis region. In certain animals such as rodents, the lack of 17alpha-hydroxylase results in the synthesis of corticosterone instead of cortisol. Steroid-producing adrenal tumours and hyperplasia of the zona fasciculata result in excess cortisol production and are the cause for adrenal Cushing's syndrome. The genetic disorder McCune-Albright syndrome can also present as Cushing's syndrome in affected patients.
Wikidata
Zona fasciculata
The zona fasciculata constitutes the middle zone of the adrenal cortex, sitting directly beneath the zona glomerulosa. Constituent cells are organized into bundles or "fascicles". The zona fasciculata chiefly produces glucocorticoids, which regulates the metabolism of glucose, especially in times of stress, it is stimulated by the hormone Adrenocorticotropic Hormone which is released from the anterior portion of the pituitary and axised upon this adrenal gland. This tissue also generates a small amount of weak androgens. The main source of androgens will come from the zona reticularis region. In certain animals such as rodents, the lack of 17alpha-hydroxylase results in the synthesis of corticosterone instead of cortisol. Steroid-producing adrenal tumours and hyperplasia of the zona fasciculata result in excess cortisol production and are the cause for adrenal Cushing's syndrome. The genetic disorder McCune-Albright syndrome can also present Cushing's syndrome in affected patients.
U.S. National Library of Medicine
Zona Fasciculata
The wide middle zone of the adrenal cortex. This zone produces a series of enzymes that convert PREGNENOLONE to cortisol (HYDROCORTISONE) via 17-ALPHA-HYDROXYPROGESTERONE.
Numerology
Chaldean Numerology
The numerical value of zona fasciculata in Chaldean Numerology is: 9
Pythagorean Numerology
The numerical value of zona fasciculata in Pythagorean Numerology is: 8
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"zona fasciculata." Definitions.net. STANDS4 LLC, 2024. Web. 28 Mar. 2024. <https://www.definitions.net/definition/zona+fasciculata>.
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