What does zidovudine mean?

Definitions for zidovudine
zaɪˈdoʊ vyuˌdinzi·dovu·dine

Here are all the possible meanings and translations of the word zidovudine.

Princeton's WordNet

  1. zidovudine, Retrovir, ZDV, AZT(noun)

    an antiviral drug (trade name Retrovir) used in the treatment of AIDS; adverse side effects include liver damage and suppression of the bone marrow


  1. zidovudine(Noun)

    A nucleoside analog reverse transcriptase inhibitor, a type of antiretroviral drug, the first approved treatment for HIV.


  1. Zidovudine

    Zidovudine or azidothymidine is a nucleoside analog reverse-transcriptase inhibitor, a type of antiretroviral drug used for the treatment of HIV/AIDS infection. AZT is the first U.S. government-approved treatment for HIV therapy, prescribed under the name Retrovir. AZT was the first breakthrough in AIDS therapy, significantly reducing the replication of the virus in patients and leading to clinical and immunologic improvements. It can also be used to prevent HIV transmission, such as from mother to child during the period of birth or after a needle stick. Used by itself in HIV-infected patients, AZT safely slows HIV replication in patients, but generally does not stop it entirely. This may allow HIV to become AZT-resistant over time, and for this reason AZT is usually used in conjunction with the other anti-HIV drugs in combination therapy called highly active antiretroviral therapy. To simplify its use in combination, AZT is included in Combivir and Trizivir, among others. Zidovudine is included in the World Health Organization's Model List of Essential Medicines, which suggests the minimum medicinal needs for a basic health care system.

U.S. National Library of Medicine

  1. Zidovudine

    A dideoxynucleoside compound in which the 3'-hydroxy group on the sugar moiety has been replaced by an azido group. This modification prevents the formation of phosphodiester linkages which are needed for the completion of nucleic acid chains. The compound is a potent inhibitor of HIV replication, acting as a chain-terminator of viral DNA during reverse transcription. It improves immunologic function, partially reverses the HIV-induced neurological dysfunction, and improves certain other clinical abnormalities associated with AIDS. Its principal toxic effect is dose-dependent suppression of bone marrow, resulting in anemia and leukopenia.

How to pronounce zidovudine?

  1. Alex
    US English

How to say zidovudine in sign language?

  1. zidovudine


  1. Chaldean Numerology

    The numerical value of zidovudine in Chaldean Numerology is: 1

  2. Pythagorean Numerology

    The numerical value of zidovudine in Pythagorean Numerology is: 3

Images & Illustrations of zidovudine

  1. zidovudinezidovudinezidovudinezidovudinezidovudine

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"zidovudine." Definitions.net. STANDS4 LLC, 2019. Web. 18 Aug. 2019. <https://www.definitions.net/definition/zidovudine>.

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