What does zalcitabine mean?
Definitions for zalcitabine
zal·citabine
This dictionary definitions page includes all the possible meanings, example usage and translations of the word zalcitabine.
Princeton's WordNet
dideoxycytosine, ddC, DDC, zalcitabinenoun
an antiviral drug used to combat HIV infection
Wiktionary
zalcitabinenoun
The compound 2'-3'-dideoxycytidine, a nucleoside analog reverse transcriptase inhibitor, formerly used in antiretroviral therapy
Wikipedia
Zalcitabine
Zalcitabine (2′-3′-dideoxycytidine, ddC), also called dideoxycytidine, is a nucleoside analog reverse-transcriptase inhibitor (NRTI) sold under the trade name Hivid. Zalcitabine was the third antiretroviral to be approved by the Food and Drug Administration (FDA) for the treatment of HIV/AIDS. It is used as part of a combination regimen. Zalcitabine appears less potent than some other nucleoside RTIs, has an inconvenient three-times daily frequency and is associated with serious adverse events. For these reasons it is now rarely used to treat human immunodeficiency virus (HIV), and it has even been removed from pharmacies entirely in some countries.
ChatGPT
zalcitabine
Zalcitabine is a type of antiviral medication that belongs to a class of drugs known as nucleoside reverse transcriptase inhibitors (NRTIs). It is used in the treatment of HIV infection by preventing the virus from multiplying in the body. It was marketed under the brand name Hivid, which is now discontinued.
Wikidata
Zalcitabine
Zalcitabine, also called dideoxycytidine, is a nucleoside analog reverse transcriptase inhibitor sold under the trade name Hivid. The recommended dosage is 0.750 mg every 8 hours, as part of a combination regimen. Zalcitabine appears less potent than some other nucleoside RTIs, has an inconvenient three-times daily frequency and is associated with serious adverse events. For these reasons it is now rarely used to treat human immunodeficiency virus, and even removed from pharmacies entirely in some countries.
U.S. National Library of Medicine
Zalcitabine
A dideoxynucleoside compound in which the 3'-hydroxy group on the sugar moiety has been replaced by a hydrogen. This modification prevents the formation of phosphodiester linkages which are needed for the completion of nucleic acid chains. The compound is a potent inhibitor of HIV replication at low concentrations, acting as a chain-terminator of viral DNA by binding to reverse transcriptase. Its principal toxic side effect is axonal degeneration resulting in peripheral neuropathy.
Matched Categories
Numerology
Chaldean Numerology
The numerical value of zalcitabine in Chaldean Numerology is: 6
Pythagorean Numerology
The numerical value of zalcitabine in Pythagorean Numerology is: 3
Popularity rank by frequency of use
Translation
Find a translation for the zalcitabine definition in other languages:
Select another language:
- - Select -
- 简体中文 (Chinese - Simplified)
- 繁體中文 (Chinese - Traditional)
- Español (Spanish)
- Esperanto (Esperanto)
- 日本語 (Japanese)
- Português (Portuguese)
- Deutsch (German)
- العربية (Arabic)
- Français (French)
- Русский (Russian)
- ಕನ್ನಡ (Kannada)
- 한국어 (Korean)
- עברית (Hebrew)
- Gaeilge (Irish)
- Українська (Ukrainian)
- اردو (Urdu)
- Magyar (Hungarian)
- मानक हिन्दी (Hindi)
- Indonesia (Indonesian)
- Italiano (Italian)
- தமிழ் (Tamil)
- Türkçe (Turkish)
- తెలుగు (Telugu)
- ภาษาไทย (Thai)
- Tiếng Việt (Vietnamese)
- Čeština (Czech)
- Polski (Polish)
- Bahasa Indonesia (Indonesian)
- Românește (Romanian)
- Nederlands (Dutch)
- Ελληνικά (Greek)
- Latinum (Latin)
- Svenska (Swedish)
- Dansk (Danish)
- Suomi (Finnish)
- فارسی (Persian)
- ייִדיש (Yiddish)
- հայերեն (Armenian)
- Norsk (Norwegian)
- English (English)
Word of the Day
Would you like us to send you a FREE new word definition delivered to your inbox daily?
Citation
Use the citation below to add this definition to your bibliography:
Style:MLAChicagoAPA
"zalcitabine." Definitions.net. STANDS4 LLC, 2024. Web. 28 Mar. 2024. <https://www.definitions.net/definition/zalcitabine>.
Discuss these zalcitabine definitions with the community:
Report Comment
We're doing our best to make sure our content is useful, accurate and safe.
If by any chance you spot an inappropriate comment while navigating through our website please use this form to let us know, and we'll take care of it shortly.
Attachment
You need to be logged in to favorite.
Log In