Definitions for wilson's disease
wil·son's dis·ease

Princeton's WordNetRate this definition:0.0 / 0 votes

1. hepatolenticular degeneration, Wilson's diseasenoun

   a rare inherited disorder of copper metabolism; copper accumulates in the liver and then in the red blood cells and brain

WikipediaRate this definition:0.0 / 0 votes

1. Wilson's disease

   Wilson's disease is a genetic disorder in which excess copper builds up in the body. Symptoms are typically related to the brain and liver. Liver-related symptoms include vomiting, weakness, fluid build up in the abdomen, swelling of the legs, yellowish skin and itchiness. Brain-related symptoms include tremors, muscle stiffness, trouble in speaking, personality changes, anxiety, and psychosis.Wilson's disease is caused by a mutation in the Wilson disease protein (ATP7B) gene. This protein transports excess copper into bile, where it is excreted in waste products. The condition is autosomal recessive; for a person to be affected, they must inherit a mutated copy of the gene from both parents. Diagnosis may be difficult and often involves a combination of blood tests, urine tests and a liver biopsy. Genetic testing may be used to screen family members of those affected.Wilson's disease is typically treated with dietary changes and medication. Dietary changes involve eating a low-copper diet and not using copper cookware. Medications used include chelating agents such as trientine and d-penicillamine and zinc supplements. Complications of Wilson's disease can include liver failure, liver cancer and kidney problems. A liver transplant may be helpful to those for whom other treatments are not effective or if liver failure occurs.Wilson's disease occurs in about 1 in 30,000 people. Symptoms usually begin between the ages of 5 and 35 years. It was first described in 1854 by a German pathologist Friedrich Theodor von Frerichs and is named after British neurologist Samuel Wilson.

ChatGPTRate this definition:0.0 / 0 votes

1. wilson's disease

   Wilson's disease is a rare inherited disorder that causes excessive amounts of copper to accumulate in the body, leading to various health problems. Copper plays a key role in developing healthy nerves, bones, and collagen. However, in Wilson's disease, the body is unable to properly metabolize and dispose of copper, leading to its buildup in organs like the liver and brain. This condition can cause hepatic disease, neurological problems, psychiatric symptoms, and a characteristic brown ring around the cornea of the eye known as a Kayser-Fleischer ring. Treatment generally involves medications to reduce copper levels, manage symptoms, and prevent damage to organs.

WikidataRate this definition:0.0 / 0 votes

1. Wilson's disease

   Wilson's disease or hepatolenticular degeneration is an autosomal recessive genetic disorder in which copper accumulates in tissues; this manifests as neurological or psychiatric symptoms and liver disease. It is treated with medication that reduces copper absorption or removes the excess copper from the body, but occasionally a liver transplant is required. The condition is due to mutations in the Wilson disease protein gene. A single abnormal copy of the gene is present in 1 in 100 people, who do not develop any symptoms. If a child inherits the gene from both parents, the child may develop Wilson's disease. Symptoms usually appear between the ages of 6 and 20 years, but cases in much older people have been described. Wilson's disease occurs in 1 to 4 per 100,000 people. Wilson's disease is named after Samuel Alexander Kinnier Wilson, the British neurologist who first described the condition in 1912.

Matched Categories

1. • Genetic Disease

How to pronounce wilson's disease?

1. Alex

   US English

   David

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   Mark

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   Daniel

   British

   Libby

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   Mia

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   Karen

   Australian

   Hayley

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   Priya

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   Neerja

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   Zira

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   Oliver

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   Wendy

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   Fred

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   Tessa

   South African

How to say wilson's disease in sign language?

Numerology

1. Chaldean Numerology

   The numerical value of wilson's disease in Chaldean Numerology is: 5

2. Pythagorean Numerology

   The numerical value of wilson's disease in Pythagorean Numerology is: 2

References

1. ^ Princeton's WordNet
   http://wordnetweb.princeton.edu/perl/webwn?s=wilson's disease
2. ^ Wikipedia
   https://en.wikipedia.org/wiki/Wilson'S_Disease
3. ^ ChatGPT
   https://chat.openai.com
4. ^ Wikidata
   https://www.wikidata.org/w/index.php?search=wilson's disease