Definitions for von Willebrand Disease
von wille·brand dis·ease

WiktionaryRate this definition:0.0 / 0 votes

1. von Willebrand diseasenoun

   An hereditary disease, characterized by a tendency to hemorrhage, and caused by a defect in blood platelet activity.

WikipediaRate this definition:0.0 / 0 votes

1. Von Willebrand disease

   Von Willebrand disease (VWD) is the most common hereditary blood-clotting disorder in humans. An acquired form can sometimes result from other medical conditions. It arises from a deficiency in the quality or quantity of von Willebrand factor (VWF), a multimeric protein that is required for platelet adhesion. It is known to affect several breeds of dogs as well as humans. The three forms of VWD are hereditary, acquired, and pseudo or platelet type. The three types of hereditary VWD are VWD type 1, VWD type 2, and VWD type 3. Type 2 contains various subtypes. Platelet type VWD is also an inherited condition.In 2008 a new diagnostic category of "Low VWF" was proposed to include those individuals whose von Willebrand factor levels were below the normal reference range but not low enough to be von Willebrand disease (levels in the 30-50 IU/dL range). Patients with low VWF can experience bleeding, despite mild reductions in VWF levels.VWD type 1 is the most common type of the disorder, with mild bleeding symptoms such as nosebleeds, though occasionally more severe symptoms can occur. Blood type can affect the presentation and severity of symptoms of VWD.VWD type 2 is the second most common type of the disorder and has mild to moderate symptoms. The factor is named after the Finnish physician Erik Adolf von Willebrand who first described the condition in 1926. Guidelines for the diagnosis and management of VWD were updated in 2021.

WikidataRate this definition:0.0 / 0 votes

1. Von Willebrand disease

   Von Willebrand disease is the most common hereditary coagulation abnormality described in humans, although it can also be acquired as a result of other medical conditions. It arises from a qualitative or quantitative deficiency of von Willebrand factor, a multimeric protein that is required for platelet adhesion. It is known to affect humans and dogs, and rarely swine, cattle, horses, and cats. There are three forms of vWD: inherited, acquired and pseudo or platelet type. There are three types of hereditary vWD: vWD Type I, vWD Type II and vWD III. Within the three inherited types of vWD there are various subtypes. Platelet type vWD is also an inherited condition. vWD Type I is the most common type of the disorder and those that have it are typically asymptomatic or may experience mild symptoms such as nosebleeds although there may be severe symptoms in some cases. There are various factors that affect the presentation and severity of symptoms of vWD such as blood type. vWD is named after Erik Adolf von Willebrand, a Finnish pediatrician who first described the disease in 1926.

How to pronounce von Willebrand Disease?

1. Alex

   US English

   David

   US English

   Mark

   US English

   Daniel

   British

   Libby

   British

   Mia

   British

   Karen

   Australian

   Hayley

   Australian

   Natasha

   Australian

   Veena

   Indian

   Priya

   Indian

   Neerja

   Indian

   Zira

   US English

   Oliver

   British

   Wendy

   British

   Fred

   US English

   Tessa

   South African

How to say von Willebrand Disease in sign language?

Numerology

1. Chaldean Numerology

   The numerical value of von Willebrand Disease in Chaldean Numerology is: 9

2. Pythagorean Numerology

   The numerical value of von Willebrand Disease in Pythagorean Numerology is: 6

References

1. ^ Wiktionary
   https://en.wiktionary.org/wiki/Von_Willebrand_Disease
2. ^ Wikipedia
   https://en.wikipedia.org/wiki/Von_Willebrand_Disease
3. ^ Wikidata
   https://www.wikidata.org/w/index.php?search=von Willebrand Disease