Definitions for valproic acid
val·proic acid

Princeton's WordNetRate this definition:0.0 / 0 votes

1. valproic acid, Depokenenoun

   anticonvulsant (trade name Depokene) used to prevent some kinds of seizures

WiktionaryRate this definition:0.0 / 0 votes

1. valproic acidnoun

   The aliphatic carboxylic acid 2-propylpentanoic acid that is used as an anticonvulsant in the treatment of epilepsy etc

WikipediaRate this definition:0.0 / 0 votes

1. Valproic acid

   Valproate (VPA) and its valproic acid, sodium valproate, and valproate semisodium forms are medications primarily used to treat epilepsy and bipolar disorder and prevent migraine headaches. They are useful for the prevention of seizures in those with absence seizures, partial seizures, and generalized seizures. They can be given intravenously or by mouth, and the tablet forms exist in both long- and short-acting formulations.Common side effects of valproate include nausea, vomiting, somnolence, and dry mouth. Serious side effects can include liver failure, and regular monitoring of liver function tests is therefore recommended. Other serious risks include pancreatitis and an increased suicide risk. Valproate is known to cause serious abnormalities in fetuses if taken during pregnancy, and is contra-indicated for women of childbearing age unless the drug is essential to their medical condition. As of 2022 the drug was still prescribed in the UK to potentially pregnant women, but use declined by 51% from 2018–19 to 2020–21.Valproate's precise mechanism of action is unclear. Proposed mechanisms include affecting GABA levels, blocking voltage-gated sodium channels, and inhibiting histone deacetylases. Valproic acid is a branched short-chain fatty acid (SCFA) made from valeric acid.Valproate was first made in 1881 and came into medical use in 1962. It is on the World Health Organization's List of Essential Medicines and is available as a generic medication. In 2020, it was the 109th most commonly prescribed medication in the United States, with more than 6 million prescriptions.

ChatGPTRate this definition:0.0 / 0 votes

1. valproic acid

   Valproic acid is a type of medication primarily used to treat seizures and bipolar disorder and to prevent migraine headaches. It is known as an anti-convulsant or anti-epileptic drug and works by restoring the balance of certain natural substances in the brain. This medication comes in different forms including capsules, liquid, or injections and it's often used in combination with other medications. Side effects can include nausea, drowsiness, or dizziness, among others.

WikidataRate this definition:0.0 / 0 votes

1. Valproic acid

   Valproic acid, an acidic chemical compound, has found clinical use as an anticonvulsant and mood-stabilizing drug, primarily in the treatment of epilepsy, bipolar disorder, and, less commonly, major depression. It is also used to treat migraine headaches and schizophrenia. VPA is a liquid at room temperature, but it can be reacted with a base such as sodium hydroxide to form the salt sodium valproate, which is a solid. The acid, salt, or a mixture of the two are marketed under the various brand names Depakote, Depakote ER, Depakene, Depakene Crono, Depacon, Depakine, Valparin and Stavzor. Approved uses of the various formulations vary by country; e.g., valproate semisodium is used as a mood stabilizer and also in the US as an anticonvulsant. VPA is a histone deacetylase inhibitor and is under investigation for treatment of HIV and various cancers.

U.S. National Library of MedicineRate this definition:0.0 / 0 votes

1. Valproic Acid

   A fatty acid with anticonvulsant properties used in the treatment of epilepsy. The mechanisms of its therapeutic actions are not well understood. It may act by increasing GAMMA-AMINOBUTYRIC ACID levels in the brain or by altering the properties of voltage dependent sodium channels.

Matched Categories

1. • Anticonvulsant

How to pronounce valproic acid?

1. Alex

   US English

   David

   US English

   Mark

   US English

   Daniel

   British

   Libby

   British

   Mia

   British

   Karen

   Australian

   Hayley

   Australian

   Natasha

   Australian

   Veena

   Indian

   Priya

   Indian

   Neerja

   Indian

   Zira

   US English

   Oliver

   British

   Wendy

   British

   Fred

   US English

   Tessa

   South African

How to say valproic acid in sign language?

Numerology

1. Chaldean Numerology

   The numerical value of valproic acid in Chaldean Numerology is: 4

2. Pythagorean Numerology

   The numerical value of valproic acid in Pythagorean Numerology is: 5

Examples of valproic acid in a Sentence

1. David Ficker:

   We've been concerned about valproic acid for many years.

2. David Ficker:

   Definitely in the epilepsy physician community, we are well aware of the risks of valproic acid during pregnancy. I think even in the neurology community.

References

1. ^ Princeton's WordNet
   http://wordnetweb.princeton.edu/perl/webwn?s=valproic acid
2. ^ Wiktionary
   https://en.wiktionary.org/wiki/Valproic_Acid
3. ^ Wikipedia
   https://en.wikipedia.org/wiki/Valproic_Acid
4. ^ ChatGPT
   https://chat.openai.com
5. ^ Wikidata
   https://www.wikidata.org/w/index.php?search=valproic acid