Definitions for trisomy 21
tri·somy 21

Princeton's WordNetRate this definition:0.0 / 0 votes

1. mongolism, mongolianism, Down's syndrome, Down syndrome, trisomy 21noun

   a congenital disorder caused by having an extra 21st chromosome; results in a flat face and short stature and mental retardation

WiktionaryRate this definition:0.0 / 0 votes

1. trisomy 21noun

   The presence of three copies of the 21st chromosome in the karyotype.

WikipediaRate this definition:0.0 / 0 votes

1. trisomy 21

   Down syndrome or Down's syndrome, also known as trisomy 21, is a genetic disorder caused by the presence of all or part of a third copy of chromosome 21. It is usually associated with physical growth delays, mild to moderate intellectual disability, and characteristic facial features. The average IQ of a young adult with Down syndrome is 50, equivalent to the mental ability of an eight- or nine-year-old child, but this can vary widely.The parents of the affected individual are usually genetically normal. The probability increases from less than 0.1% in 20-year-old mothers to 3% in those of age 45. The extra chromosome is believed to occur by chance, with no known behavioral activity or environmental factor that changes the probability. Down syndrome can be identified during pregnancy by prenatal screening followed by diagnostic testing or after birth by direct observation and genetic testing. Since the introduction of screening, Down syndrome pregnancies are often aborted (rates varying from 50%-85% depending on maternal age, gestational age, and maternal race/ethnicity).There is no cure for Down syndrome. Education and proper care have been shown to improve quality of life. Some children with Down syndrome are educated in typical school classes, while others require more specialized education. Some individuals with Down syndrome graduate from high school, and a few attend post-secondary education. In adulthood, about 20% in the United States do paid work in some capacity, with many requiring a sheltered work environment. Support in financial and legal matters is often needed. Life expectancy is around 50 to 60 years in the developed world with proper health care. Regular screening for health problems common in Down syndrome is recommended throughout the person's life.Down syndrome is one of the most common chromosome abnormalities in humans. It occurs in about 1 in 1,000 babies born each year. In 2015, Down syndrome was present in 5.4 million individuals globally and resulted in 27,000 deaths, down from 43,000 deaths in 1990. It is named after British doctor John Langdon Down, who fully described the syndrome in 1866. Some aspects of the condition were described earlier by French psychiatrist Jean-Étienne Dominique Esquirol in 1838 and French physician Édouard Séguin in 1844. The genetic cause of Down syndrome was discovered in 1959.

ChatGPTRate this definition:0.0 / 0 votes

1. trisomy 21

   Trisomy 21, also known as Down syndrome, is a genetic disorder caused by the presence of all or part of a third copy (hence 'trisomy') of chromosome 21 in a person's cells. This is one of the most common chromosomal abnormalities in humans. It is typically associated with physical growth delays, characteristic facial features, and mild to moderate intellectual disability. The risk of having a child with Down syndrome increases with the mother's age.

WikidataRate this definition:0.0 / 0 votes

1. Trisomy 21

   A chromosomal abnormality consisting of the presence of a third copy of chromosome 21 in somatic cells.

Matched Categories

1. • Birth Defect
   • Trisomy

How to pronounce trisomy 21?

1. Alex

   US English

   David

   US English

   Mark

   US English

   Daniel

   British

   Libby

   British

   Mia

   British

   Karen

   Australian

   Hayley

   Australian

   Natasha

   Australian

   Veena

   Indian

   Priya

   Indian

   Neerja

   Indian

   Zira

   US English

   Oliver

   British

   Wendy

   British

   Fred

   US English

   Tessa

   South African

How to say trisomy 21 in sign language?

Numerology

1. Chaldean Numerology

   The numerical value of trisomy 21 in Chaldean Numerology is: 4

2. Pythagorean Numerology

   The numerical value of trisomy 21 in Pythagorean Numerology is: 2

References

1. ^ Princeton's WordNet
   http://wordnetweb.princeton.edu/perl/webwn?s=trisomy 21
2. ^ Wiktionary
   https://en.wiktionary.org/wiki/Trisomy_21
3. ^ Wikipedia
   https://en.wikipedia.org/wiki/Trisomy_21
4. ^ ChatGPT
   https://chat.openai.com
5. ^ Wikidata
   https://www.wikidata.org/w/index.php?search=trisomy 21