What does trastuzumab mean?

Definitions for trastuzumab
trastuzum·ab

This dictionary definitions page includes all the possible meanings, example usage and translations of the word trastuzumab.

Wiktionary

  1. trastuzumabnoun

    A drug used in the treatment of breast cancer which targets the HER-2 oncogene.

Wikidata

  1. Trastuzumab

    Trastuzumab is a monoclonal antibody that interferes with the HER2/neu receptor. Its main use is to treat certain breast cancers. The HER receptors are proteins that are embedded in the cell membrane and communicate molecular signals from outside the cell to inside the cell, and turn genes on and off. The HER proteins stimulate cell proliferation. In some cancers, notably certain types of breast cancer, HER2 is over-expressed, and causes cancer cells to reproduce uncontrollably. The original studies of trastuzumab showed that it improved overall survival in late-stage breast cancer from 20.3 to 25.1 months. In early stage breast cancer, it reduces the risk of cancer returning after surgery by an absolute risk of 9.5%, and the risk of death by an absolute risk of 3% however increases serious heart problems by an absolute risk of 2.1% which may resolve if treatment is stopped. Trastuzumab is controversial partly because of its cost, as much as $54,000 per year, and while certain private insurance companies in the U.S. and government health care systems in Canada, UK and elsewhere have refused to pay for trastuzumab for certain patients, some companies have since accepted trastuzumab treatment as a covered preventative treatment.

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Numerology

  1. Chaldean Numerology

    The numerical value of trastuzumab in Chaldean Numerology is: 4

  2. Pythagorean Numerology

    The numerical value of trastuzumab in Pythagorean Numerology is: 9

Examples of trastuzumab in a Sentence

  1. Andrew Dillon:

    In order to be able to recommend pertuzumab as an addition to trastuzumab and chemotherapy, the committee needed to have more evidence of its long-term clinical benefits, particularly its impact on overall survival.

Popularity rank by frequency of use

trastuzumab#100000#117781#333333

Translations for trastuzumab

From our Multilingual Translation Dictionary

  • ட்ரஸ்டுசூமாப்Tamil

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"trastuzumab." Definitions.net. STANDS4 LLC, 2024. Web. 7 Oct. 2024. <https://www.definitions.net/definition/trastuzumab>.

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