Definitions for tizanidine
ti·zani·dine

WiktionaryRate this definition:0.0 / 0 votes

1. tizanidinenoun

   A particular drug used as a muscle relaxant.

WikipediaRate this definition:0.0 / 0 votes

1. Tizanidine

   Tizanidine, sold under the brand name Zanaflex among others, is an alpha-2 (α2) adrenergic receptor agonist, similar to clonidine, that is used to treat muscle spasticity due to spinal cord injury, multiple sclerosis, and spastic cerebral palsy. Effectiveness appears similar to baclofen or diazepam. It is taken by mouth.Common side effects of tizanidine include dry mouth, sleepiness, weakness, and dizziness. Serious side effects may include low blood pressure, liver problems, psychosis, and QT prolongation. It is unclear if use in pregnancy and breastfeeding is safe. It is an α2-adrenergic agonist, but how it works is not entirely clear.Tizanidine was approved for medical use in the United States in 1996. It is available as a generic medication. In 2020, it was the 84th most commonly prescribed medication in the United States, with more than 8 million prescriptions.

WikidataRate this definition:0.0 / 0 votes

1. Tizanidine

   Tizanidine is a drug that is used as a muscle relaxant. It is a centrally acting α2 adrenergic agonist. It is used to treat the spasms, cramping, and tightness of muscles caused by medical problems such as multiple sclerosis, ALS, spastic diplegia, back pain, or certain other injuries to the spine or central nervous system. It is also prescribed off-label for migraine headaches, as a sleep aid, and as an anticonvulsant. It is also prescribed for some symptoms of fibromyalgia. Tizanidine has been found to be as effective as other antispasmodic drugs and has superior tolerability to that of baclofen and diazepam. Tizanidine may cause hypotension, so caution is advised when it is used in patients who have a history of orthostatic hypotension. Use caution with this drug as it can be very strong even at the 2 mg dose. Also use caution when switching from gel cap to tablet form and vice versa. Tizanidine can occasionally cause liver damage, generally the hepatocellular type. Clinical trials show that up to 5% of patients treated with tizanidine had elevated liver function test values, though symptoms disappeared upon withdrawal of the drug. Care should be used when first beginning treatment with tizanidine with regular liver tests for the first 6 months of treatment.

Anagrams for tizanidine »

1. nizatidine

How to pronounce tizanidine?

1. Alex

   US English

   David

   US English

   Mark

   US English

   Daniel

   British

   Libby

   British

   Mia

   British

   Karen

   Australian

   Hayley

   Australian

   Natasha

   Australian

   Veena

   Indian

   Priya

   Indian

   Neerja

   Indian

   Zira

   US English

   Oliver

   British

   Wendy

   British

   Fred

   US English

   Tessa

   South African

How to say tizanidine in sign language?

Numerology

1. Chaldean Numerology

   The numerical value of tizanidine in Chaldean Numerology is: 7

2. Pythagorean Numerology

   The numerical value of tizanidine in Pythagorean Numerology is: 3

Popularity rank by frequency of use

References

1. ^ Wiktionary
   https://en.wiktionary.org/wiki/Tizanidine
2. ^ Wikipedia
   https://en.wikipedia.org/wiki/Tizanidine
3. ^ Wikidata
   https://www.wikidata.org/w/index.php?search=tizanidine