What does tianeptine mean?
Definitions for tianeptine
tianep·tine
This dictionary definitions page includes all the possible meanings, example usage and translations of the word tianeptine.
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Wiktionary
tianeptinenoun
An SSRE drug used to treat major depressive episodes, indicated as a thymoleptic.
Wikidata
Tianeptine
Tianeptine was discovered by The French Society of Medical Research in the 1960s. Under the trade-names it is a drug used for treating major depressive episodes. It has structural similarities to the tricyclic antidepressants, but it has different pharmacological properties. Tianeptine is a selective serotonin reuptake enhancer, opposite to the action of SSRIs. One review points to the cancellative effects of tianeptine and fluoxetine coadministration on serotonin reuptake. Another suggests that long-term administration of tianeptine has no effect on serotonin pathways. Tianeptine enhances the extracellular concentration of dopamine in the nucleus accumbens and modulates the D2 and D3 dopamine receptors. There is also action on the NMDA and AMPA receptors. Recent reviews point to this pathway as a hypothesized mechanism of action, based on tianeptine's effect of reversing impaired neuroplasticity associated with stress. Tianeptine reduces the effects of serotonin in the limbic system and the pre-frontal cortex, giving rise to a mood elevation, unlike the mood blunting associated with SSRIs. Like SSRIs, however, tianeptine's onset-of-action delay is approximately 2–6 weeks with improvements sometimes noticeable in as soon as one week. Its short-lived, but pleasant, stimulant effect experienced by some patients is shared with its predecessor, amineptine, whose side effects related to dopamine uptake inhibitor activity resulted in Servier's research into tianeptine. Suggested dosage is three times daily, due to its short duration of action.
Numerology
Chaldean Numerology
The numerical value of tianeptine in Chaldean Numerology is: 3
Pythagorean Numerology
The numerical value of tianeptine in Pythagorean Numerology is: 5
Translations for tianeptine
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- 噻奈普汀Chinese
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"tianeptine." Definitions.net. STANDS4 LLC, 2024. Web. 28 Mar. 2024. <https://www.definitions.net/definition/tianeptine>.
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