What does thenoyltrifluoroacetone mean?
Definitions for thenoyltrifluoroacetone
thenoyl·tri·flu·o·roace·tone
This dictionary definitions page includes all the possible meanings, example usage and translations of the word thenoyltrifluoroacetone.
Wikidata
Thenoyltrifluoroacetone
Thenoyltrifluoroacetone, C8H5F3O2S, is a chemical compound used pharmacologically as a chelating agent. It is an inhibitor of cellular respiration by blocking the respiratory chain at complex II. Perhaps the first report of TTFA as an inhibitor of respiration was by A. L. Tappel in 1960. Tappel had the idea that inhibitors like antimycin and alkyl hydroxyquinoline-N-oxide might work by chelating iron in the hydrophobic mileau of respiratory membrane proteins, so he tested a series of hydrophobic chelating agents. TTFA was a potent inhibitor, but not because of its chelating ability. TTFA binds at the quinone reduction site in Complex II, preventing ubiquinone from binding. The first x-ray structure of Complex II showing how TTFA binds, 1ZP0, was published in 2005 .
U.S. National Library of Medicine
Thenoyltrifluoroacetone
Chelating agent and inhibitor of cellular respiration.
Numerology
Chaldean Numerology
The numerical value of thenoyltrifluoroacetone in Chaldean Numerology is: 1
Pythagorean Numerology
The numerical value of thenoyltrifluoroacetone in Pythagorean Numerology is: 8
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"thenoyltrifluoroacetone." Definitions.net. STANDS4 LLC, 2024. Web. 25 Apr. 2024. <https://www.definitions.net/definition/thenoyltrifluoroacetone>.
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