Definitions for structural genomics
struc·tural genomics

Princeton's WordNetRate this definition:0.0 / 0 votes

1. structural genomicsnoun

   the branch of genomics that determines the three-dimensional structures of proteins

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1. structural genomics

   Structural genomics is a branch of genomics that involves the characterization and providing three-dimensional structures of all the proteins produced by a particular organism, or genome. This field of study aims to develop a comprehensive understanding of the relationship between the structure and function of a protein and its role in the biology of the organism. Structural genomics can also provides insights into the function of genes and possible avenues for drug discovery.

WikidataRate this definition:0.0 / 0 votes

1. Structural genomics

   Structural genomics seeks to describe the 3-dimensional structure of every protein encoded by a given genome. This genome-based approach allows for a high-throughput method of structure determination by a combination of experimental and modeling approaches. The principal difference between structural genomics and traditional structural prediction is that structural genomics attempts to determine the structure of every protein encoded by the genome, rather than focusing on one particular protein. With full-genome sequences available, structure prediction can be done more quickly through a combination of experimental and modeling approaches, especially because the availability of large number of sequenced genomes and previously-solved protein structures allows scientists to model protein structure on the structures of previously solved homologs. Because protein structure is closely linked with protein function, the structural genomics has the potential to inform knowledge of protein function. In addition to elucidating protein functions, structural genomics can be used to identify novel protein folds and potential targets for drug discovery. Structural genomics involves taking a large number of approaches to structure determination, including experimental methods using genomic sequences or modeling-based approaches based on sequence or structural homology to a protein of known structure or based on chemical and physical principles for a protein with no homology to any known structure.

Matched Categories

1. • Genomics

How to pronounce structural genomics?

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Numerology

1. Chaldean Numerology

   The numerical value of structural genomics in Chaldean Numerology is: 2

2. Pythagorean Numerology

   The numerical value of structural genomics in Pythagorean Numerology is: 4

References

1. ^ Princeton's WordNet
   http://wordnetweb.princeton.edu/perl/webwn?s=structural genomics
2. ^ ChatGPT
   https://chat.openai.com
3. ^ Wikidata
   https://www.wikidata.org/w/index.php?search=structural genomics