What does stem-cell research mean?

Definitions for stem-cell research
stem-cell research

This dictionary definitions page includes all the possible meanings, example usage and translations of the word stem-cell research.

Princeton's WordNet

  1. stem-cell researchnoun

    research on stem cells and their use in medicine

Wikipedia

  1. stem-cell research

    In multicellular organisms, stem cells are undifferentiated or partially differentiated cells that can differentiate into various types of cells and proliferate indefinitely to produce more of the same stem cell. They are the earliest type of cell in a cell lineage. They are found in both embryonic and adult organisms, but they have slightly different properties in each. They are usually distinguished from progenitor cells, which cannot divide indefinitely, and precursor or blast cells, which are usually committed to differentiating into one cell type. In mammals, roughly 50–150 cells make up the inner cell mass during the blastocyst stage of embryonic development, around days 5–14. These have stem-cell capability. In vivo, they eventually differentiate into all of the body's cell types (making them pluripotent). This process starts with the differentiation into the three germ layers – the ectoderm, mesoderm and endoderm – at the gastrulation stage. However, when they are isolated and cultured in vitro, they can be kept in the stem-cell stage and are known as embryonic stem cells (ESCs). Adult stem cells are found in a few select locations in the body, known as niches, such as those in the bone marrow or gonads. They exist to replenish rapidly lost cell types and are multipotent or unipotent, meaning they only differentiate into a few cell types or one type of cell. In mammals, they include, among others, hematopoietic stem cells, which replenish blood and immune cells, basal cells, which maintain the skin epithelium, and mesenchymal stem cells, which maintain bone, cartilage, muscle and fat cells. Adult stem cells are a small minority of cells; they are vastly outnumbered by the progenitor cells and terminally differentiated cells that they differentiate into.Research into stem cells grew out of findings by Canadian biologists Ernest McCulloch, James Till and Andrew J. Becker at the University of Toronto and the Ontario Cancer Institute in the 1960s. As of 2016, the only established medical therapy using stem cells is hematopoietic stem cell transplantation, first performed in 1958 by French oncologist Georges Mathé. Since 1998 however, it has been possible to culture and differentiate human embryonic stem cells (in stem-cell lines). The process of isolating these cells has been controversial, because it typically results in the destruction of the embryo. Sources for isolating ESCs have been restricted in some European countries and Canada, but others such as the UK and China have promoted the research. Somatic cell nuclear transfer is a cloning method that can be used to create a cloned embryo for the use of its embryonic stem cells in stem cell therapy. In 2006, a Japanese team led by Shinya Yamanaka discovered a method to convert mature body cells back into stem cells. These were termed induced pluripotent stem cells (iPSCs).

ChatGPT

  1. stem-cell research

    Stem cell research refers to the scientific study and exploration of stem cells, which are undifferentiated or 'blank' cells capable of developing into various types of specific cells with specialized functions. This research is conducted to understand the fundamental properties of stem cells, their formation and differentiation process, and to discover potential therapeutic uses for treating various diseases and medical conditions, such as cancer, spinal cord injuries, Parkinson's disease, and more, through cell-based therapies and regenerative medicine. It also includes areas like cloning and genetic engineering. However, stem cell research often raises ethical issues as embryonic stem cells are frequently used.

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Numerology

  1. Chaldean Numerology

    The numerical value of stem-cell research in Chaldean Numerology is: 2

  2. Pythagorean Numerology

    The numerical value of stem-cell research in Pythagorean Numerology is: 4

Examples of stem-cell research in a Sentence

  1. Bernie Sanders:

    No matter your party or political ideology, this is a sad day for America. Nancy Reagan was an exemplary first lady, a devoted partner, she was her husband's most trusted adviser and, as such, served our country well. Even after her time in the White House, she was an outspoken advocate for stem-cell research to find a cure for Alzheimer's. Nancy Reagan had a good heart, and she will be dearly missed.

  2. Jimmy Carter:

    Rosalynn and I are saddened by the passing of former First Lady Nancy Reagan. She will always be admired for her strength of conviction and her lifelong devotion to her husband, her 'just say no' campaign prevented many young people from falling prey to the allure of drug use; and her advocacy for stem cell research raised public awareness and influenced decision makers about vital research for Alzheimer's disease. We extend our condolences to her family at this difficult time.

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"stem-cell research." Definitions.net. STANDS4 LLC, 2024. Web. 28 Mar. 2024. <https://www.definitions.net/definition/stem-cell+research>.

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