What does squalamine mean?
Definitions for squalamine
squalamine
This dictionary definitions page includes all the possible meanings, example usage and translations of the word squalamine.
Did you actually mean squall line or saxicoline?
Wiktionary
squalaminenoun
A broad-spectrum antibiotic derived from the livers of dogfish
Wikipedia
Squalamine
Squalamine is a steroid-polyamine conjugate compound with broad spectrum antimicrobial activity and anti-angiogenic activity. It was studied as a potential cancer drug and as a potential treatment for wet macular degeneration but as of 2018 had not succeeded in Phase III trials for any use.
Wikidata
Squalamine
Squalamine is an aminosterol compound with potent broad spectrum antimicobial activity discovered in the tissues of the dogfish shark by a team led by Dr. Michael Zasloff Dr. Zasloff searched the tissues of the dogfish for compounds that might help explain the hardiness of this animal to infection, despite its "primitive" immune system. Using techniques that Zasloff's team had developed to isolate and identify antimicrobial peptides from animal tissues, the team extracted and characterized a novel bile acid like compound containing a polyamine, never before seen in nature. The compound was called "squalamine", based on its source, and its chemical structure. Further analyses of larger quantities of dogfish liver extracts revealed squalamine to be the most abundant member of a larger aminosterol family, comprising at least 12 related compounds. One of these, "MSI-1436" or "Trodusquamine", although structurally similar to squalamine, and also quite potent as an anti-infective, exhibits a profoundly different pharmacology in vertebrates, causing weight loss and adipose tissue mobilization. Squalamine is sometimes confused with the similar sounding squalene, an unrelated compound also found in shark-liver.
Numerology
Chaldean Numerology
The numerical value of squalamine in Chaldean Numerology is: 3
Pythagorean Numerology
The numerical value of squalamine in Pythagorean Numerology is: 4
Translation
Find a translation for the squalamine definition in other languages:
Select another language:
- - Select -
- 简体中文 (Chinese - Simplified)
- 繁體中文 (Chinese - Traditional)
- Español (Spanish)
- Esperanto (Esperanto)
- 日本語 (Japanese)
- Português (Portuguese)
- Deutsch (German)
- العربية (Arabic)
- Français (French)
- Русский (Russian)
- ಕನ್ನಡ (Kannada)
- 한국어 (Korean)
- עברית (Hebrew)
- Gaeilge (Irish)
- Українська (Ukrainian)
- اردو (Urdu)
- Magyar (Hungarian)
- मानक हिन्दी (Hindi)
- Indonesia (Indonesian)
- Italiano (Italian)
- தமிழ் (Tamil)
- Türkçe (Turkish)
- తెలుగు (Telugu)
- ภาษาไทย (Thai)
- Tiếng Việt (Vietnamese)
- Čeština (Czech)
- Polski (Polish)
- Bahasa Indonesia (Indonesian)
- Românește (Romanian)
- Nederlands (Dutch)
- Ελληνικά (Greek)
- Latinum (Latin)
- Svenska (Swedish)
- Dansk (Danish)
- Suomi (Finnish)
- فارسی (Persian)
- ייִדיש (Yiddish)
- հայերեն (Armenian)
- Norsk (Norwegian)
- English (English)
Word of the Day
Would you like us to send you a FREE new word definition delivered to your inbox daily?
Citation
Use the citation below to add this definition to your bibliography:
Style:MLAChicagoAPA
"squalamine." Definitions.net. STANDS4 LLC, 2025. Web. 14 Jan. 2025. <https://www.definitions.net/definition/squalamine>.
Discuss these squalamine definitions with the community:
Report Comment
We're doing our best to make sure our content is useful, accurate and safe.
If by any chance you spot an inappropriate comment while navigating through our website please use this form to let us know, and we'll take care of it shortly.
Attachment
You need to be logged in to favorite.
Log In