What does somatic hypermutation mean?
Definitions for somatic hypermutation
so·mat·ic hy·per·mu·ta·tion
This dictionary definitions page includes all the possible meanings, example usage and translations of the word somatic hypermutation.
Wikipedia
Somatic hypermutation
Somatic hypermutation (or SHM) is a cellular mechanism by which the immune system adapts to the new foreign elements that confront it (e.g. microbes), as seen during class switching. A major component of the process of affinity maturation, SHM diversifies B cell receptors used to recognize foreign elements (antigens) and allows the immune system to adapt its response to new threats during the lifetime of an organism. Somatic hypermutation involves a programmed process of mutation affecting the variable regions of immunoglobulin genes. Unlike germline mutation, SHM affects only an organism's individual immune cells, and the mutations are not transmitted to the organism's offspring. Because this mechanism is merely selective and not precisely targeted, somatic hypermutation has been strongly implicated in the development of B-cell lymphomas and many other cancers.
Wikidata
Somatic hypermutation
Somatic hypermutation is a cellular mechanism by which the immune system adapts to the new foreign elements that confront it. A major component of the process of affinity maturation, SHM diversifies B cell receptors used to recognize foreign elements and allows the immune system to adapt its response to new threats during the lifetime of an organism. Somatic hypermutation involves a programmed process of mutation affecting the variable regions of immunoglobulin genes. Unlike germline mutation, SHM affects only individual immune cells, and the mutations are not transmitted to offspring. Mistargeted somatic hypermutation is a likely mechanism in the development of B-cell lymphomas.
Numerology
Chaldean Numerology
The numerical value of somatic hypermutation in Chaldean Numerology is: 4
Pythagorean Numerology
The numerical value of somatic hypermutation in Pythagorean Numerology is: 4
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"somatic hypermutation." Definitions.net. STANDS4 LLC, 2024. Web. 17 Apr. 2024. <https://www.definitions.net/definition/somatic+hypermutation>.
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