What does sickle cell disease mean?

Definitions for sickle cell disease
sick·le cell dis·ease

Here are all the possible meanings and translations of the word sickle cell disease.

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  1. Sickle cell disease

    Sickle-cell disease, or sickle-cell anaemia or drepanocytosis, is a hereditary blood disorder, characterized by red blood cells that assume an abnormal, rigid, sickle shape. Sickling decreases the cells' flexibility and results in a risk of various complications. The sickling occurs because of a mutation in the haemoglobin gene. Individuals with one copy of the defunct gene display both normal and abnormal haemoglobin. This is an example of codominance. Life expectancy is shortened. In 1994, in the US, the average life expectancy of persons with this condition was estimated to be 42 years in males and 48 years in females, but today, thanks to better management of the disease, patients can live into their 70s or beyond. Sickle-cell disease occurs more commonly among people whose ancestors lived in tropical and sub-tropical sub-saharan regions where malaria is or was common. Where malaria is common, carrying a single sickle-cell gene confers a fitness. Specifically, humans with one of the two alleles of sickle-cell disease show less severe symptoms when infected with malaria. Sickle-cell anaemia is a form of sickle-cell disease in which there is homozygosity for the mutation that causes HbS. Sickle-cell anaemia is also referred to as "HbSS", "SS disease", "haemoglobin S" or permutations of those names. In heterozygous people, that is, those who have only one sickle gene and one normal adult haemoglobin gene, the condition is referred to as "HbAS" or "sickle cell trait". Other, rarer forms of sickle-cell disease are compound heterozygous states in which the person has only one copy of the mutation that causes HbS and one copy of another abnormal haemoglobin allele. They include sickle-haemoglobin C disease, sickle beta-plus-thalassaemia and sickle beta-zero-thalassaemia.

How to pronounce sickle cell disease?

  1. Alex
    Alex
    US English
    Daniel
    Daniel
    British
    Karen
    Karen
    Australian
    Veena
    Veena
    Indian

How to say sickle cell disease in sign language?

  1. sicklecelldisease

Numerology

  1. Chaldean Numerology

    The numerical value of sickle cell disease in Chaldean Numerology is: 8

  2. Pythagorean Numerology

    The numerical value of sickle cell disease in Pythagorean Numerology is: 9

Images & Illustrations of sickle cell disease

  1. sickle cell diseasesickle cell diseasesickle cell diseasesickle cell diseasesickle cell disease

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"sickle cell disease." Definitions.net. STANDS4 LLC, 2020. Web. 4 Jul 2020. <https://www.definitions.net/definition/sickle+cell+disease>.

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