What does rovelizumab mean?

Definitions for rovelizumab
rov·elizum·ab

This dictionary definitions page includes all the possible meanings, example usage and translations of the word rovelizumab.

Wiktionary

  1. rovelizumabnoun

    A humanized monoclonal antibody that was an experimental immunosuppressive drug intended to treat patients suffering from haemorrhagic shock by suppressing white blood cells.

Wikidata

  1. Rovelizumab

    Rovelizumab, also known as LeukArrest and Hu23F2G, is a humanized monoclonal antibody which was an experimental immunosuppressive drug. Rovelizumab was developed by Icos to treat patients suffering from haemorrhagic shock. The drug is a monoclonal antibody that suppresses white blood cells which become overly active during shock. During testing the number of patients given the drug was low because rovelizumab had to be delivered within four hours of the injury and consent was required. Often the patient was unconscious and relatives had to be reached to give consent. In June 1998, Icos and many medical centers asked the United States Food and Drug Administration to waive consent requirements in situations where the patient was at high risk of dying and relatives could not be reached. While some medical ethicists opposed waiving consent, the FDA approved the proposal in August 1998 for five medical centers. Development of rovelizumab was halted in April 2000 when interim data from phase III clinical trials did not meet Icos's goals. The company's goals for rovelizumab included reducing the chance of multiple organ failure and reducing the death-rate from shock at 28 days. Rovelizumab was also being tested for treating heart attack, multiple sclerosis, and stroke, and was being explored as a treatment for cerebral vasospasm, head trauma, kidney transplantation, and restenosis.

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Numerology

  1. Chaldean Numerology

    The numerical value of rovelizumab in Chaldean Numerology is: 8

  2. Pythagorean Numerology

    The numerical value of rovelizumab in Pythagorean Numerology is: 9

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"rovelizumab." Definitions.net. STANDS4 LLC, 2024. Web. 25 Apr. 2024. <https://www.definitions.net/definition/rovelizumab>.

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