What does reelin mean?

Definitions for reelin
reel·in

Here are all the possible meanings and translations of the word reelin.

Wiktionary

  1. reelin(Noun)

    A protein that helps to regulate processes of neuronal migration and positioning in the developing brain.

    Etymology: from the abnormal gait of reeler mice, later found to be deficient in this protein.

Freebase

  1. Reelin

    Reelin is a large secreted extracellular matrix glycoprotein that helps regulate processes of neuronal migration and positioning in the developing brain by controlling cell–cell interactions. Besides this important role in early development, reelin continues to work in the adult brain. It modulates synaptic plasticity by enhancing the induction and maintenance of long-term potentiation. It also stimulates dendrite and dendritic spine development and regulates the continuing migration of neuroblasts generated in adult neurogenesis sites like subventricular and subgranular zones. It is found not only in the brain, but also in the spinal cord, blood, and other body organs and tissues. Reelin has been suggested to be implicated in pathogenesis of several brain diseases. The expression of the protein has been found to be significantly lower in schizophrenia and psychotic bipolar disorder, but the cause of this observation remains uncertain as studies show that psychotropic medication itself affects reelin expression. Moreover, the epigenetic hypothesis aimed at explaining the changed levels has received some contradictory evidence. Total lack of reelin causes a form of lissencephaly. Reelin may also play a role in Alzheimer's disease, temporal lobe epilepsy and autism.

How to pronounce reelin?

  1. Alex
    Alex
    US English
    Daniel
    Daniel
    British
    Karen
    Karen
    Australian
    Veena
    Veena
    Indian

How to say reelin in sign language?

  1. reelin

Numerology

  1. Chaldean Numerology

    The numerical value of reelin in Chaldean Numerology is: 3

  2. Pythagorean Numerology

    The numerical value of reelin in Pythagorean Numerology is: 9

Images & Illustrations of reelin

  1. reelin

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