What does reeler mean?

Definitions for reeler
reel·er

This dictionary definitions page includes all the possible meanings, example usage and translations of the word reeler.

Princeton's WordNet

  1. staggerer, totterer, reelernoun

    someone who walks unsteadily as if about to fall

  2. reelernoun

    a dancer of reels

Wikipedia

  1. Reeler

    A reeler is a mouse mutant, so named because of its characteristic "reeling" gait. This is caused by the profound underdevelopment of the mouse's cerebellum, a segment of the brain responsible for locomotion. The mutation is autosomal and recessive, and prevents the typical cerebellar folia from forming. Cortical neurons are generated normally but are abnormally placed, resulting in disorganization of cortical laminar layers in the central nervous system. The reason is the lack of Reelin, an extracellular matrix glycoprotein, which, during the corticogenesis, is secreted mainly by the Cajal-Retzius cells. In the reeler neocortex, cortical plate neurons are aligned in a practically inverted fashion (‘‘outside-in’’). In the ventricular zone of the cortex fewer neurons have been found to have radial glial processes. In the dentate gyrus of hippocampus, no characteristic radial glial scaffold is formed and no compact granule cell layer is established. Therefore, the reeler mouse presents a good model in which to investigate the mechanisms of establishment of the precise neuronal network during development.

ChatGPT

  1. reeler

    A reeler is a machine or device that is designed for winding or reeling material such as thread, wire, film or rope. This term can also describe an individual who operates such equipment. In some contexts, the term "reeler" may also refer to an organism, usually a mutant, showing uncoordinated movements, often referring to certain genetically-modified laboratory mice.

Webster Dictionary

  1. Reelernoun

    one who reels

  2. Reelernoun

    the grasshopper warbler; -- so called from its note

Freebase

  1. Reeler

    A reeler is a mouse mutant, so named because of its characteristic "reeling" gait. This is caused by profound hypoplasia of the mouse's cerebellum, in which the normal cerebellar folia are missing. The mutation is autosomal and recessive. Cortical neurons are generated normally but are abnormally placed, resulting in disorganization of cortical laminar layers in the CNS. The reason is the lack of Reelin, an extracellular matrix glycoprotein, which during the corticogenesis is secreted mainly by the Cajal-Retzius cells. In the reeler neocortex, cortical plate neurons are aligned in a practically inverted fashion. In the ventricular zone of the cortex fewer neurons have been found to have radial glial processes. In the dentate gyrus of hippocampus, no characteristic radial glial scaffold is formed and no compact granule cell layer is established. Therefore, the reeler mouse presents a good model in which to investigate the mechanisms of establishment of the precise neuronal network during development.

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Numerology

  1. Chaldean Numerology

    The numerical value of reeler in Chaldean Numerology is: 4

  2. Pythagorean Numerology

    The numerical value of reeler in Pythagorean Numerology is: 9

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"reeler." Definitions.net. STANDS4 LLC, 2023. Web. 10 Dec. 2023. <https://www.definitions.net/definition/reeler>.

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