What does proteasome mean?

Definitions for proteasome
pro·tea·some

Here are all the possible meanings and translations of the word proteasome.

Wiktionary

  1. proteasome(Noun)

    A complex protein, found in bacterial, archeal and eukaryotic cells, that breaks down other proteins via proteolysis.

Freebase

  1. Proteasome

    Proteasomes are protein complexes inside all eukaryotes and archaea, and in some bacteria. In eukaryotes, they are located in the nucleus and the cytoplasm. The main function of the proteasome is to degrade unneeded or damaged proteins by proteolysis, a chemical reaction that breaks peptide bonds. Enzymes that carry out such reactions are called proteases. Proteasomes are part of a major mechanism by which cells regulate the concentration of particular proteins and degrade misfolded proteins. The degradation process yields peptides of about seven to eight amino acids long, which can then be further degraded into shorter amino acid sequences and used in synthesizing new proteins. Proteins are tagged for degradation with a small protein called ubiquitin. The tagging reaction is catalyzed by enzymes called ubiquitin ligases. Once a protein is tagged with a single ubiquitin molecule, this is a signal to other ligases to attach additional ubiquitin molecules. The result is a polyubiquitin chain that is bound by the proteasome, allowing it to degrade the tagged protein. In structure, the proteasome is a cylindrical complex containing a "core" of four stacked rings forming a central pore. Each ring is composed of seven individual proteins. The inner two rings are made of seven β subunits that contain three to seven protease active sites. These sites are located on the interior surface of the rings, so that the target protein must enter the central pore before it is degraded. The outer two rings each contain seven α subunits whose function is to maintain a "gate" through which proteins enter the barrel. These α subunits are controlled by binding to "cap" structures or regulatory particles that recognize polyubiquitin tags attached to protein substrates and initiate the degradation process. The overall system of ubiquitination and proteasomal degradation is known as the ubiquitin-proteasome system.

How to pronounce proteasome?

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How to say proteasome in sign language?

  1. proteasome

Numerology

  1. Chaldean Numerology

    The numerical value of proteasome in Chaldean Numerology is: 1

  2. Pythagorean Numerology

    The numerical value of proteasome in Pythagorean Numerology is: 1

Images & Illustrations of proteasome

  1. proteasomeproteasomeproteasomeproteasomeproteasome

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Translations for proteasome

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"proteasome." Definitions.net. STANDS4 LLC, 2019. Web. 16 Jul 2019. <https://www.definitions.net/definition/proteasome>.

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