What does proprotein convertases mean?
Definitions for proprotein convertases
pro·pro·tein con·ver·tases
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Wikipedia
proprotein convertases
Proprotein convertases (PPCs) are a family of proteins that activate other proteins. Many proteins are inactive when they are first synthesized, because they contain chains of amino acids that block their activity. Proprotein convertases remove those chains and activate the protein. The prototypical proprotein convertase is furin. Proprotein convertases have medical significance, because they are involved in many important biological processes, such as cholesterol synthesis. Compounds called proprotein convertase inhibitors can block their action, and block the target proteins from becoming active. Many proprotein convertases, especially furin and PACE4, are involved in pathological processes such as viral infection, inflammation, hypercholesterolemia, and cancer, and have been postulated as therapeutic targets for some of these diseases.
U.S. National Library of Medicine
Proprotein Convertases
Proteolytic enzymes that are involved in the conversion of protein precursors such as peptide prohormones into PEPTIDE HORMONES. Some are ENDOPEPTIDASES, some are EXOPEPTIDASES.
Numerology
Chaldean Numerology
The numerical value of proprotein convertases in Chaldean Numerology is: 3
Pythagorean Numerology
The numerical value of proprotein convertases in Pythagorean Numerology is: 8
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"proprotein convertases." Definitions.net. STANDS4 LLC, 2024. Web. 19 Apr. 2024. <https://www.definitions.net/definition/proprotein+convertases>.
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