Definitions for progeria
proʊˈdʒɪər i əpro·ge·ri·a

Princeton's WordNetRate this definition:5.0 / 1 vote

1. progerianoun

   a rare abnormality marked by premature aging (grey hair and wrinkled skin and stooped posture) in a child

WiktionaryRate this definition:0.0 / 0 votes

1. progerianoun

   An extremely rare genetic condition wherein symptoms resembling aspects of aging are manifested at an early age.

WikipediaRate this definition:0.0 / 0 votes

1. Progeria

   Progeria is a specific type of progeroid syndrome, also known as Hutchinson–Gilford syndrome. A single gene mutation is responsible for progeria. The gene, known as lamin A (LMNA), makes a protein necessary for holding the nucleus of the cell together. When this gene gets mutated an abnormal form of lamin A protein called progerin is produced. Progeroid syndromes are a group of diseases that causes individuals to age faster than usual, leading to them appearing older than they actually are. Patients born with progeria typically live to an age of mid-teens to early twenties.Severe cardiovascular complications usually develop by puberty, resulting in death.

ChatGPTRate this definition:0.0 / 0 votes

1. progeria

   Progeria, also known as Hutchinson-Gilford progeria syndrome, is a rare and fatal genetic condition that causes children to age rapidly, beginning in their first two years of life. Symptoms include growth failure, loss of body fat and hair, aged-looking skin, stiffness of joints, and cardiovascular disease. It is caused by a mutation in the LMNA gene, which makes the protein lamin A, an essential component of the structural scaffolding that holds the nucleus of a cell together. There is currently no cure for progeria.

WikidataRate this definition:0.0 / 0 votes

1. Progeria

   Progeria, Hutchinson Gilford Progeria Syndrome, or Progeria syndrome is an extremely rare genetic disease wherein symptoms resembling aspects of aging are manifested at a very early age. The word progeria comes from the Greek words "pro", meaning "before" or "premature", and "gēras", meaning "old age". The disorder has a very low incident rate, occurring in an estimated 1 per 8 million live births. Those born with progeria typically live to their mid teens and early twenties. It is a genetic condition that occurs as a new mutation, and is rarely inherited. Although the term progeria applies strictly speaking to all diseases characterized by premature aging symptoms, and is often used as such, it is often applied specifically in reference to Hutchinson-Gilford Progeria Syndrome. Scientists are particularly interested in progeria because it might reveal clues about the normal process of aging. Progeria was first described in 1886 by Jonathan Hutchinson. It was also described independently in 1897 by Hastings Gilford. The condition was later named Hutchinson-Gilford Progeria Syndrome.

U.S. National Library of MedicineRate this definition:0.0 / 0 votes

1. Progeria

   An abnormal congenital condition, associated with defects in the LAMIN TYPE A gene, which is characterized by premature aging in children, where all the changes of cell senescence occur. It is manifested by premature greying; hair loss; hearing loss (DEAFNESS); cataracts (CATARACT); ARTHRITIS; OSTEOPOROSIS; DIABETES MELLITUS; atrophy of subcutaneous fat; skeletal hypoplasia; elevated urinary HYALURONIC ACID; and accelerated ATHEROSCLEROSIS. Many affected individuals develop malignant tumors, especially SARCOMA.

Matched Categories

1. • Abnormality

How to pronounce progeria?

1. Alex

   US English

   David

   US English

   Mark

   US English

   Daniel

   British

   Libby

   British

   Mia

   British

   Karen

   Australian

   Hayley

   Australian

   Natasha

   Australian

   Veena

   Indian

   Priya

   Indian

   Neerja

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   Zira

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   Oliver

   British

   Wendy

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   Fred

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   Tessa

   South African

How to say progeria in sign language?

Numerology

1. Chaldean Numerology

   The numerical value of progeria in Chaldean Numerology is: 2

2. Pythagorean Numerology

   The numerical value of progeria in Pythagorean Numerology is: 8

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References

1. ^ Princeton's WordNet
   http://wordnetweb.princeton.edu/perl/webwn?s=progeria
2. ^ Wiktionary
   https://en.wiktionary.org/wiki/Progeria
3. ^ Wikipedia
   https://en.wikipedia.org/wiki/Progeria
4. ^ ChatGPT
   https://chat.openai.com
5. ^ Wikidata
   https://www.wikidata.org/w/index.php?search=progeria