What does pristinamycin mean?
Definitions for pristinamycin
pristi·namycin
This dictionary definitions page includes all the possible meanings, example usage and translations of the word pristinamycin.
Wiktionary
pristinamycinnoun
An antibiotic used primarily in the treatment of staphylococcal infections, and to a lesser extent streptococcal infections.
Wikidata
Pristinamycin
Pristinamycin, also spelled pristinamycine, is an antibiotic used primarily in the treatment of staphylococcal infections, and to a lesser extent streptococcal infections. It is a streptogramin group antibiotic, similar to virginiamycin, derived from the bacterium Streptomyces pristinaespiralis. It is marketed in Europe by Sanofi-Aventis under the trade name Synercid and Pyostacine. Pristinamycin is a mixture of two components that have a synergistic antibacterial action. Pristinamycin IA is a macrolide, and results in pristinamycin having a similar spectrum of action to erythromycin. Pristinamycin IIA is a depsipeptide. PI and PII are coproduced by S. pristinaespiralis in a ratio of 30:70. Each compound binds to the bacterial 50 S ribosomal subunit and inhibits the elongation process of the protein synthesis, thereby exhibiting only a moderate bacteriostatic activity. However, the combination of both substances acts synergistically and leads to a potent bactericidal activity that can reach up to 100 times that of the separate components. The pristinamycin biosynthetic gene cluster is the largest antibiotic supercluster known so far with a size of ~210 kb, where the PI and PII biosynthetic genes are not clustered individually but are scattered across the complete sequence region. Furthermore, this biosynthetic gene region is interrupted by a cryptic type II PKS gene cluster.
U.S. National Library of Medicine
Pristinamycin
An antibiotic mixture originally isolated from Streptomyces pristinaspiralis. It is a mixture of compounds from STREPTOGRAMIN GROUP A: pristinamycin IIA and IIB and from STREPTOGRAMIN GROUP B: pristinamycin IA, pristinamycin IB, pristinamycin IC.
Numerology
Chaldean Numerology
The numerical value of pristinamycin in Chaldean Numerology is: 3
Pythagorean Numerology
The numerical value of pristinamycin in Pythagorean Numerology is: 8
Translations for pristinamycin
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"pristinamycin." Definitions.net. STANDS4 LLC, 2024. Web. 19 Apr. 2024. <https://www.definitions.net/definition/pristinamycin>.
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