What does prion mean?

Definitions for prion
ˈpri ɒn, ˈpraɪ-pri·on

Here are all the possible meanings and translations of the word prion.

Princeton's WordNet

  1. prionnoun

    (microbiology) an infectious protein particle similar to a virus but lacking nucleic acid; thought to be the agent responsible for scrapie and other degenerative diseases of the nervous system

Freebase

  1. Prion

    A prion in the Scrapie form is an infectious agent composed of protein in a misfolded form. This is the central idea of the Prion Hypothesis, which remains debated. This would be in contrast to all other known infectious agents which must contain nucleic acids. The word prion, coined in 1982 by Stanley B. Prusiner, is derived from the words protein and infection. Prions are responsible for the transmissible spongiform encephalopathies in a variety of mammals, including bovine spongiform encephalopathy in cattle. In humans prions cause Creutzfeldt-Jakob Disease, variant Creutzfeldt-Jakob Disease, Gerstmann–Sträussler–Scheinker syndrome, Fatal Familial Insomnia and Kuru. All known prion diseases affect the structure of the brain or other neural tissue and all are currently untreatable and universally fatal. Prions, like viruses, are not actually alive, although both can reproduce by hijacking the functions of living cells. Prions propagate by transmitting a misfolded protein state. When a prion enters a healthy organism, it induces existing, properly folded proteins to convert into the disease-associated, prion form; the prion acts as a template to guide the misfolding of more proteins into prion form. These newly formed prions can then go on to convert more proteins themselves; this triggers a chain reaction that produces large amounts of the prion form. All known prions induce the formation of an amyloid fold, in which the protein polymerises into an aggregate consisting of tightly packed beta sheets. Amyloid aggregates are fibrils, growing at their ends, and replicating when breakage causes two growing ends to become four growing ends. The incubation period of prion diseases is determined by the exponential growth rate associated with prion replication, which is a balance between the linear growth and the breakage of aggregates. CScC

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Numerology

  1. Chaldean Numerology

    The numerical value of prion in Chaldean Numerology is: 5

  2. Pythagorean Numerology

    The numerical value of prion in Pythagorean Numerology is: 9

Examples of prion in a Sentence

  1. Simon Mead:

    We are not saying Alzheimer's is a prion disease, we are saying that it may share the fundamental mechanism that something goes rogue and spreads around the disease.

Images & Illustrations of prion

  1. prionprionprionprionprion

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